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MIR4793 microRNA 4793 [ Homo sapiens (human) ]

Gene ID: 100616112, updated on 17-Sep-2024

Summary

Official Symbol
MIR4793provided by HGNC
Official Full Name
microRNA 4793provided by HGNC
Primary source
HGNC:HGNC:41538
See related
Ensembl:ENSG00000284575 miRBase:MI0017440; AllianceGenome:HGNC:41538
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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Genomic context

See MIR4793 in Genome Data Viewer
Location:
3p21.31
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 3 NC_000003.12 (48644194..48644280, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 3 NC_060927.1 (48673154..48673240, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (48681627..48681713, complement)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene transmembrane protein 89 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:48666910-48667410 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:48667411-48667911 Neighboring gene solute carrier family 26 member 6 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14335 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14336 Neighboring gene microRNA 6824 Neighboring gene cadherin EGF LAG seven-pass G-type receptor 3 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:48693647-48694344 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:48694345-48695040 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:48698042-48698628 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:48698629-48699213 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:48700385-48700970 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19841 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19842 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:48702141-48702725 Neighboring gene long intergenic non-protein coding RNA 2585 Neighboring gene NCK interacting protein with SH3 domain Neighboring gene Sharpr-MPRA regulatory region 90

Genomic regions, transcripts, and products

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_039956.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    AC121252
    Related
    ENST00000577502.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p14 Primary Assembly

    Range
    48644194..48644280 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060927.1 Alternate T2T-CHM13v2.0

    Range
    48673154..48673240 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)