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FDFT1 farnesyl-diphosphate farnesyltransferase 1 [ Nomascus leucogenys (northern white-cheeked gibbon) ]

Gene ID: 100603333, updated on 18-Sep-2024

Summary

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Gene symbol
FDFT1
Gene description
farnesyl-diphosphate farnesyltransferase 1
See related
EnsemblRapid:ENSNLEG00000015059
Gene type
protein coding
RefSeq status
MODEL
Organism
Nomascus leucogenys
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae; Nomascus
Orthologs
human mouse all
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Genomic context

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See FDFT1 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
9
Annotation release Status Assembly Chr Location
103 current Asia_NLE_v1 (GCF_006542625.1) 4 NC_044384.1 (139557548..139594295, complement)
102 previous assembly Nleu_3.0 (GCF_000146795.2) 4 NC_019819.1 (141454398..141498268, complement)

Chromosome 4 - NC_044384.1Genomic Context describing neighboring genes Neighboring gene olfactory receptor 7E24-like Neighboring gene cathepsin B Neighboring gene activated RNA polymerase II transcriptional coactivator p15 pseudogene Neighboring gene nei like DNA glycosylase 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables squalene synthase [NAD(P)H] activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cholesterol biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in farnesyl diphosphate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
squalene synthase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Nomascus leucogenys Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Asia_NLE_v1 Primary Assembly

Genomic

  1. NC_044384.1 Reference Asia_NLE_v1 Primary Assembly

    Range
    139557548..139594295 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003271441.4 → XP_003271489.1  squalene synthase isoform X3

    See identical proteins and their annotated locations for XP_003271489.1

    UniProtKB/TrEMBL
    A0A2I3HU46, G1RYJ8
    Related
    ENSNLEP00000047057.1, ENSNLET00000044703.2
    Conserved Domains (1) summary
    TIGR01559
    Location:38 → 370
    squal_synth; farnesyl-diphosphate farnesyltransferase

  2. XM_012496860.2 → XP_012352314.1  squalene synthase isoform X5

    Conserved Domains (1) summary
    cl00210
    Location:22 → 203
    Isoprenoid_Biosyn_C1; Isoprenoid Biosynthesis enzymes, Class 1

  3. XM_012496835.2 → XP_012352289.1  squalene synthase isoform X1

    UniProtKB/TrEMBL
    G1RYJ8
    Related
    ENSNLEP00000018325.4, ENSNLET00000019236.4
    Conserved Domains (1) summary
    TIGR01559
    Location:100 → 432
    squal_synth; farnesyl-diphosphate farnesyltransferase

  4. XM_030812370.1 → XP_030668230.1  squalene synthase isoform X4

    Conserved Domains (1) summary
    cl00210
    Location:38 → 311
    Isoprenoid_Biosyn_C1; Isoprenoid Biosynthesis enzymes, Class 1

  5. XM_030812369.1 → XP_030668229.1  squalene synthase isoform X2

    UniProtKB/TrEMBL
    G1RYJ8
    Conserved Domains (1) summary
    cl00210
    Location:100 → 373
    Isoprenoid_Biosyn_C1; Isoprenoid Biosynthesis enzymes, Class 1
Nucleotide Protein
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