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MASP1 MBL associated serine protease 1 [ Nomascus leucogenys (northern white-cheeked gibbon) ]

Gene ID: 100601109, updated on 8-Mar-2024

Summary

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Gene symbol
MASP1
Gene description
MBL associated serine protease 1
See related
EnsemblRapid:ENSNLEG00000006685
Gene type
protein coding
RefSeq status
MODEL
Organism
Nomascus leucogenys
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae; Nomascus
Orthologs
human mouse all
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Genomic context

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See MASP1 in Genome Data Viewer
Location:
chromosome: 11
Exon count:
18
Annotation release Status Assembly Chr Location
103 current Asia_NLE_v1 (GCF_006542625.1) 11 NC_044391.1 (108358449..108434054, complement)
102 previous assembly Nleu_3.0 (GCF_000146795.2) 11 NC_019826.1 (112098251..112174909, complement)

Chromosome 11 - NC_044391.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein L39 like Neighboring gene uncharacterized LOC105740507 Neighboring gene receptor transporter protein 1 Neighboring gene uncharacterized LOC105740544 Neighboring gene receptor transporter protein 4 Neighboring gene uncharacterized LOC115837368

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in complement activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in zymogen activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in blood microparticle IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
mannan-binding lectin serine protease 1
Names
mannan binding lectin serine peptidase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Nomascus leucogenys Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Asia_NLE_v1 Primary Assembly

Genomic

  1. NC_044391.1 Reference Asia_NLE_v1 Primary Assembly

    Range
    108358449..108434054 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003256630.2 → XP_003256678.2  mannan-binding lectin serine protease 1 isoform X2

    UniProtKB/TrEMBL
    A0A2I3GQD9
    Related
    ENSNLEP00000033541.2, ENSNLET00000036111.2
    Conserved Domains (6) summary
    cd00033
    Location:301 → 363
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    PHA02639
    Location:300 → 433
    PHA02639; EEV host range protein; Provisional
    cd00041
    Location:28 → 137
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    cd00190
    Location:449 → 694
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam00431
    Location:185 → 294
    CUB; CUB domain
    pfam14670
    Location:153 → 181
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  2. XM_003256628.2 → XP_003256676.1  mannan-binding lectin serine protease 1 isoform X1

    UniProtKB/TrEMBL
    A0A2I3GNR6
    Related
    ENSNLEP00000032993.1, ENSNLET00000046638.2
    Conserved Domains (6) summary
    cd00033
    Location:301 → 363
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    PHA02639
    Location:300 → 433
    PHA02639; EEV host range protein; Provisional
    smart00020
    Location:449 → 711
    Tryp_SPc; Trypsin-like serine protease
    cd00041
    Location:28 → 137
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam00431
    Location:185 → 294
    CUB; CUB domain
    pfam14670
    Location:153 → 181
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  3. XM_003256629.3 → XP_003256677.1  mannan-binding lectin serine protease 1 isoform X3

    UniProtKB/TrEMBL
    G1R4M8
    Related
    ENSNLEP00000008150.2, ENSNLET00000008537.3
    Conserved Domains (4) summary
    cd00033
    Location:301 → 363
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    cd00041
    Location:28 → 137
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam00431
    Location:185 → 294
    CUB; CUB domain
    pfam14670
    Location:153 → 181
    FXa_inhibition; Coagulation Factor Xa inhibitory site
Nucleotide Protein
Heading Accession and Version

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