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PLCB1 phospholipase C beta 1 [ Nomascus leucogenys (northern white-cheeked gibbon) ]

Gene ID: 100597115, updated on 8-Mar-2024

Summary

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Gene symbol
PLCB1
Gene description
phospholipase C beta 1
See related
EnsemblRapid:ENSNLEG00000014158
Gene type
protein coding
RefSeq status
MODEL
Organism
Nomascus leucogenys
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae; Nomascus
Orthologs
human mouse all
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Genomic context

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See PLCB1 in Genome Data Viewer
Location:
chromosome: 11
Exon count:
36
Annotation release Status Assembly Chr Location
103 current Asia_NLE_v1 (GCF_006542625.1) 11 NC_044391.1 (2505524..3293143)
102 previous assembly Nleu_3.0 (GCF_000146795.2) 11 NC_019826.1 (2600854..3374245)

Chromosome 11 - NC_044391.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105740463 Neighboring gene thioredoxin related transmembrane protein 4 Neighboring gene small nucleolar RNA SNORA73 family Neighboring gene phospholipase C beta 4 Neighboring gene lysosomal associated membrane protein family member 5 Neighboring gene p21 (RAC1) activated kinase 5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calmodulin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol phospholipase C activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in lipid catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in memory IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nuclear speck IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Nomascus leucogenys Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Asia_NLE_v1 Primary Assembly

Genomic

  1. NC_044391.1 Reference Asia_NLE_v1 Primary Assembly

    Range
    2505524..3293143
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030821960.1 → XP_030677820.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X3

    UniProtKB/TrEMBL
    A0A2I3HFW9
    Related
    ENSNLEP00000042533.2, ENSNLET00000055861.2
    Conserved Domains (6) summary
    cd00275
    Location:677 → 796
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:316 → 643
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:22 → 148
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16208
    Location:153 → 303
    EFh_PI-PLCbeta1; EF-hand motif found in phosphoinositide phospholipase C beta 1 (PI-PLC-beta1)
    pfam06631
    Location:903 → 939
    DUF1154; Protein of unknown function (DUF1154)
    pfam08703
    Location:1003 → 1141
    PLC-beta_C; PLC-beta C terminal

  2. XM_003252590.4 → XP_003252638.2  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X3

    UniProtKB/TrEMBL
    A0A2I3HFW9
    Conserved Domains (6) summary
    cd00275
    Location:677 → 796
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:316 → 643
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:22 → 148
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16208
    Location:153 → 303
    EFh_PI-PLCbeta1; EF-hand motif found in phosphoinositide phospholipase C beta 1 (PI-PLC-beta1)
    pfam06631
    Location:903 → 939
    DUF1154; Protein of unknown function (DUF1154)
    pfam08703
    Location:1003 → 1141
    PLC-beta_C; PLC-beta C terminal

  3. XM_003252589.3 → XP_003252637.2  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1

    UniProtKB/TrEMBL
    G1RVN2
    Related
    ENSNLEP00000017309.3, ENSNLET00000018174.3
    Conserved Domains (6) summary
    cd00275
    Location:677 → 796
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:316 → 643
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:22 → 148
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16208
    Location:153 → 303
    EFh_PI-PLCbeta1; EF-hand motif found in phosphoinositide phospholipase C beta 1 (PI-PLC-beta1)
    pfam06631
    Location:903 → 939
    DUF1154; Protein of unknown function (DUF1154)
    pfam08703
    Location:1003 → 1172
    PLC-beta_C; PLC-beta C terminal

  4. XM_030821961.1 → XP_030677821.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X4

    UniProtKB/TrEMBL
    G1RVN2

  5. XM_030821959.1 → XP_030677819.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X2

    UniProtKB/TrEMBL
    G1RVN2
Nucleotide Protein
Heading Accession and Version

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