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PI4KA phosphatidylinositol 4-kinase alpha [ Nomascus leucogenys (northern white-cheeked gibbon) ]

Gene ID: 100596626, updated on 8-Mar-2024

Summary

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Gene symbol
PI4KA
Gene description
phosphatidylinositol 4-kinase alpha
See related
EnsemblRapid:ENSNLEG00000000110
Gene type
protein coding
RefSeq status
MODEL
Organism
Nomascus leucogenys
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae; Nomascus
Orthologs
human mouse all
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Genomic context

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See PI4KA in Genome Data Viewer
Location:
chromosome: 7b
Exon count:
56
Annotation release Status Assembly Chr Location
103 current Asia_NLE_v1 (GCF_006542625.1) 7b NC_044387.1 (48118851..48266253, complement)
102 previous assembly Nleu_3.0 (GCF_000146795.2) 7b NC_019822.1 (51672684..51837387)

Chromosome 7b - NC_044387.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC115835982 Neighboring gene HIC ZBTB transcriptional repressor 2 Neighboring gene transmembrane protein 191C Neighboring gene serpin family D member 1 Neighboring gene synaptosome associated protein 29 Neighboring gene small nucleolar RNA U3 Neighboring gene CRK like proto-oncogene, adaptor protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol 4-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in phosphatidylinositol phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidylinositol 4-kinase alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Nomascus leucogenys Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Asia_NLE_v1 Primary Assembly

Genomic

  1. NC_044387.1 Reference Asia_NLE_v1 Primary Assembly

    Range
    48118851..48266253 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003281433.4 → XP_003281481.2  phosphatidylinositol 4-kinase alpha isoform X1

    UniProtKB/TrEMBL
    G1QH25
    Related
    ENSNLEP00000000207.2, ENSNLET00000000222.3
    Conserved Domains (2) summary
    cd00871
    Location:1547 → 1722
    PI4Ka; Phosphoinositide 4-kinase(PI4K), accessory domain (PIK domain); PIK domain is conserved in PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. PI4K phosphorylates hydroxylgroup at position 4 on the ...
    cd05167
    Location:1783 → 2101
    PI4Kc_III_alpha; Catalytic domain of Type III Phosphoinositide 4-kinase alpha

  2. XM_030815901.1 → XP_030671761.1  phosphatidylinositol 4-kinase alpha isoform X2

    UniProtKB/TrEMBL
    G1QH25
    Conserved Domains (1) summary
    cd00871
    Location:1547 → 1706
    PI4Ka; Phosphoinositide 4-kinase(PI4K), accessory domain (PIK domain); PIK domain is conserved in PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. PI4K phosphorylates hydroxylgroup at position 4 on the ...
Nucleotide Protein
Heading Accession and Version

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