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PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [ Nomascus leucogenys (northern white-cheeked gibbon) ]

Gene ID: 100586512, updated on 8-Mar-2024

Summary

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Gene symbol
PIK3CG
Gene description
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
See related
EnsemblRapid:ENSNLEG00000008808
Gene type
protein coding
RefSeq status
MODEL
Organism
Nomascus leucogenys
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae; Nomascus
Orthologs
human mouse all
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Genomic context

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See PIK3CG in Genome Data Viewer
Location:
chromosome: 13
Exon count:
12
Annotation release Status Assembly Chr Location
103 current Asia_NLE_v1 (GCF_006542625.1) 13 NC_044393.1 (55939512..55982034)
102 previous assembly Nleu_3.0 (GCF_000146795.2) 13 NC_019828.1 (57884453..57926604)

Chromosome 13 - NC_044393.1Genomic Context describing neighboring genes Neighboring gene nicotinamide phosphoribosyltransferase Neighboring gene coiled-coil domain containing 71 like Neighboring gene putative uncharacterized protein PRO2829 Neighboring gene protein kinase cAMP-dependent type II regulatory subunit beta

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables 1-phosphatidylinositol-4-phosphate 3-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-3-phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of phosphatidylinositol 3-kinase complex, class IA IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of phosphatidylinositol 3-kinase complex, class IB IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
Names
phosphoinositide-3-kinase, catalytic, gamma polypeptide

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Nomascus leucogenys Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Asia_NLE_v1 Primary Assembly

Genomic

  1. NC_044393.1 Reference Asia_NLE_v1 Primary Assembly

    Range
    55939512..55982034
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030825743.1 → XP_030681603.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform

    UniProtKB/TrEMBL
    G1RC26
    Related
    ENSNLEP00000032577.2, ENSNLET00000060213.2
    Conserved Domains (4) summary
    cd08399
    Location:350 → 527
    C2_PI3K_class_I_gamma; C2 domain present in class I gamma phosphatidylinositol 3-kinases (PI3Ks)
    smart00144
    Location:203 → 312
    PI3K_rbd; PI3-kinase family, Ras-binding domain
    cd00872
    Location:549 → 725
    PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
    cd00894
    Location:729 → 1095
    PI3Kc_IB_gamma; Catalytic domain of Class IB Phosphoinositide 3-kinase gamma

  2. XM_012512141.2 → XP_012367595.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform

    UniProtKB/TrEMBL
    G1RC26
    Conserved Domains (4) summary
    cd08399
    Location:350 → 527
    C2_PI3K_class_I_gamma; C2 domain present in class I gamma phosphatidylinositol 3-kinases (PI3Ks)
    smart00144
    Location:203 → 312
    PI3K_rbd; PI3-kinase family, Ras-binding domain
    cd00872
    Location:549 → 725
    PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
    cd00894
    Location:729 → 1095
    PI3Kc_IB_gamma; Catalytic domain of Class IB Phosphoinositide 3-kinase gamma
Nucleotide Protein
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