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ALOX5 arachidonate 5-lipoxygenase [ Nomascus leucogenys (northern white-cheeked gibbon) ]

Gene ID: 100584513, updated on 8-Mar-2024

Summary

Gene symbol
ALOX5
Gene description
arachidonate 5-lipoxygenase
See related
EnsemblRapid:ENSNLEG00000015960
Gene type
protein coding
RefSeq status
MODEL
Organism
Nomascus leucogenys
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae; Nomascus
Orthologs
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Genomic context

See ALOX5 in Genome Data Viewer
Location:
chromosome: 18
Exon count:
14
Annotation release Status Assembly Chr Location
103 current Asia_NLE_v1 (GCF_006542625.1) 18 NC_044398.1 (43256656..43332849)
102 previous assembly Nleu_3.0 (GCF_000146795.2) 18 NC_019833.1 (26687860..26764526)

Chromosome 18 - NC_044398.1Genomic Context describing neighboring genes Neighboring gene olfactory receptor 6C74-like Neighboring gene olfactory receptor 13A1 Neighboring gene uncharacterized LOC105739019 Neighboring gene membrane associated ring-CH-type finger 8 Neighboring gene zinc finger AN1-type containing 4

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables arachidonate 5-lipoxygenase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in linoleic acid metabolic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in lipid oxidation IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in nuclear envelope IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
arachidonate 5-lipoxygenase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Nomascus leucogenys Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Asia_NLE_v1 Primary Assembly

Genomic

  1. NC_044398.1 Reference Asia_NLE_v1 Primary Assembly

    Range
    43256656..43332849
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030798505.1XP_030654365.1  arachidonate 5-lipoxygenase

    UniProtKB/TrEMBL
    G1S1K8
    Related
    ENSNLEP00000019396.3, ENSNLET00000020377.3
    Conserved Domains (2) summary
    cd01753
    Location:2115
    PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...
    pfam00305
    Location:227665
    Lipoxygenase