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DLAT dihydrolipoamide S-acetyltransferase [ Nomascus leucogenys (northern white-cheeked gibbon) ]

Gene ID: 100581962, updated on 8-Mar-2024

Summary

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Gene symbol
DLAT
Gene description
dihydrolipoamide S-acetyltransferase
See related
EnsemblRapid:ENSNLEG00000007289
Gene type
protein coding
RefSeq status
MODEL
Organism
Nomascus leucogenys
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae; Nomascus
Orthologs
human mouse all
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Genomic context

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See DLAT in Genome Data Viewer
Location:
chromosome: 15
Exon count:
14
Annotation release Status Assembly Chr Location
103 current Asia_NLE_v1 (GCF_006542625.1) 15 NC_044395.1 (22817151..22854870, complement)
102 previous assembly Nleu_3.0 (GCF_000146795.2) 15 NC_019830.1 (23395582..23434803, complement)

Chromosome 15 - NC_044395.1Genomic Context describing neighboring genes Neighboring gene translocase of inner mitochondrial membrane 8 homolog B Neighboring gene NKAP domain containing 1 Neighboring gene PIH1 domain containing 2 Neighboring gene U6 spliceosomal RNA Neighboring gene peptidyl-prolyl cis-trans isomerase H pseudogene Neighboring gene DIX domain containing 1 Neighboring gene chromosome 15 C11orf52 homolog Neighboring gene crystallin alpha B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables dihydrolipoyllysine-residue acetyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in acetyl-CoA biosynthetic process from pyruvate IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of pyruvate dehydrogenase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Nomascus leucogenys Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Asia_NLE_v1 Primary Assembly

Genomic

  1. NC_044395.1 Reference Asia_NLE_v1 Primary Assembly

    Range
    22817151..22854870 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003253139.3 → XP_003253187.1  dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial isoform X1

    UniProtKB/TrEMBL
    G1QNQ3, G1R6S0
    Related
    ENSNLEP00000008892.1, ENSNLET00000009312.3
    Conserved Domains (2) summary
    cd06849
    Location:92 → 165
    lipoyl_domain; Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid ...
    TIGR01349
    Location:221 → 647
    PDHac_trf_mito; pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form

  2. XM_003253140.4 → XP_003253188.1  dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial isoform X3

    UniProtKB/TrEMBL
    G1QNQ3
    Conserved Domains (2) summary
    PRK11892
    Location:40 → 119
    PRK11892; pyruvate dehydrogenase subunit beta; Provisional
    TIGR01349
    Location:165 → 591
    PDHac_trf_mito; pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form

  3. XM_030828776.1 → XP_030684636.1  dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial isoform X2

    UniProtKB/TrEMBL
    G1QNQ3
    Conserved Domains (2) summary
    cd06849
    Location:78 → 123
    lipoyl_domain; Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid ...
    TIGR01349
    Location:179 → 605
    PDHac_trf_mito; pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form
Nucleotide Protein
Heading Accession and Version

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