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PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta [ Nomascus leucogenys (northern white-cheeked gibbon) ]

Gene ID: 100580872, updated on 8-Mar-2024

Summary

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Gene symbol
PIK3CD
Gene description
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
See related
EnsemblRapid:ENSNLEG00000009299
Gene type
protein coding
RefSeq status
MODEL
Organism
Nomascus leucogenys
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae; Nomascus
Orthologs
human mouse all
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Genomic context

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See PIK3CD in Genome Data Viewer
Location:
chromosome: 24
Exon count:
26
Annotation release Status Assembly Chr Location
103 current Asia_NLE_v1 (GCF_006542625.1) 24 NC_044404.1 (10481508..10555068)
102 previous assembly Nleu_3.0 (GCF_000146795.2) 24 NC_019839.1 (9587920..9676903)

Chromosome 24 - NC_044404.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 25 member 33 Neighboring gene 60S ribosomal protein L9 pseudogene Neighboring gene transmembrane protein 201 Neighboring gene putative uncharacterized protein PIK3CD-AS1 Neighboring gene calsyntenin 1 Neighboring gene small nucleolar RNA ACA64

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables 1-phosphatidylinositol-4-phosphate 3-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-3-phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of phosphatidylinositol 3-kinase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Nomascus leucogenys Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Asia_NLE_v1 Primary Assembly

Genomic

  1. NC_044404.1 Reference Asia_NLE_v1 Primary Assembly

    Range
    10481508..10555068
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030805587.1 → XP_030661447.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1

    UniProtKB/TrEMBL
    G1RDT2
    Conserved Domains (5) summary
    cd08693
    Location:314 → 481
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    smart00145
    Location:503 → 684
    PI3Ka; Phosphoinositide 3-kinase family, accessory domain (PIK domain)
    cd05174
    Location:676 → 1042
    PI3Kc_IA_delta; Catalytic domain of Class IA Phosphoinositide 3-kinase delta
    pfam00794
    Location:177 → 281
    PI3K_rbd; PI3-kinase family, ras-binding domain
    pfam02192
    Location:32 → 107
    PI3K_p85B; PI3-kinase family, p85-binding domain

  2. XM_030805593.1 → XP_030661453.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X4

    UniProtKB/TrEMBL
    G1RDT2
    Conserved Domains (5) summary
    cd08693
    Location:285 → 452
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    smart00145
    Location:474 → 655
    PI3Ka; Phosphoinositide 3-kinase family, accessory domain (PIK domain)
    cd05174
    Location:647 → 1013
    PI3Kc_IA_delta; Catalytic domain of Class IA Phosphoinositide 3-kinase delta
    pfam02192
    Location:32 → 107
    PI3K_p85B; PI3-kinase family, p85-binding domain
    cl02484
    Location:177 → 261
    PI3K_rbd; PI3-kinase family, ras-binding domain

  3. XM_030805592.1 → XP_030661452.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X3

    UniProtKB/TrEMBL
    G1RDT2
    Conserved Domains (5) summary
    cd08693
    Location:308 → 475
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    smart00145
    Location:497 → 678
    PI3Ka; Phosphoinositide 3-kinase family, accessory domain (PIK domain)
    cd05174
    Location:670 → 1036
    PI3Kc_IA_delta; Catalytic domain of Class IA Phosphoinositide 3-kinase delta
    pfam00794
    Location:177 → 275
    PI3K_rbd; PI3-kinase family, ras-binding domain
    pfam02192
    Location:32 → 107
    PI3K_p85B; PI3-kinase family, p85-binding domain

  4. XM_030805590.1 → XP_030661450.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1

    UniProtKB/TrEMBL
    G1RDT2
    Conserved Domains (5) summary
    cd08693
    Location:314 → 481
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    smart00145
    Location:503 → 684
    PI3Ka; Phosphoinositide 3-kinase family, accessory domain (PIK domain)
    cd05174
    Location:676 → 1042
    PI3Kc_IA_delta; Catalytic domain of Class IA Phosphoinositide 3-kinase delta
    pfam00794
    Location:177 → 281
    PI3K_rbd; PI3-kinase family, ras-binding domain
    pfam02192
    Location:32 → 107
    PI3K_p85B; PI3-kinase family, p85-binding domain

  5. XM_030805591.1 → XP_030661451.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X2

    UniProtKB/TrEMBL
    G1RDT2
    Related
    ENSNLEP00000054872.1, ENSNLET00000070121.1
    Conserved Domains (5) summary
    cd08693
    Location:314 → 481
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    smart00145
    Location:505 → 683
    PI3Ka; Phosphoinositide 3-kinase family, accessory domain (PIK domain)
    cd05174
    Location:675 → 1041
    PI3Kc_IA_delta; Catalytic domain of Class IA Phosphoinositide 3-kinase delta
    pfam00794
    Location:177 → 281
    PI3K_rbd; PI3-kinase family, ras-binding domain
    pfam02192
    Location:32 → 107
    PI3K_p85B; PI3-kinase family, p85-binding domain

  6. XM_030805589.1 → XP_030661449.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1

    UniProtKB/TrEMBL
    G1RDT2
    Related
    ENSNLEP00000049410.1, ENSNLET00000076696.1
    Conserved Domains (5) summary
    cd08693
    Location:314 → 481
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    smart00145
    Location:503 → 684
    PI3Ka; Phosphoinositide 3-kinase family, accessory domain (PIK domain)
    cd05174
    Location:676 → 1042
    PI3Kc_IA_delta; Catalytic domain of Class IA Phosphoinositide 3-kinase delta
    pfam00794
    Location:177 → 281
    PI3K_rbd; PI3-kinase family, ras-binding domain
    pfam02192
    Location:32 → 107
    PI3K_p85B; PI3-kinase family, p85-binding domain

  7. XM_030805594.1 → XP_030661454.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X5

Nucleotide Protein
Heading Accession and Version

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