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ALOX5 arachidonate 5-lipoxygenase [ Meleagris gallopavo (turkey) ]

Gene ID: 100542129, updated on 8-Mar-2024

Summary

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Gene symbol
ALOX5
Gene description
arachidonate 5-lipoxygenase
See related
Ensembl:ENSMGAG00000007690
Gene type
protein coding
RefSeq status
MODEL
Organism
Meleagris gallopavo
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Meleagridinae; Meleagris
Orthologs
human mouse all
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Genomic context

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See ALOX5 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
14
Annotation release Status Assembly Chr Location
103 current Turkey_5.1 (GCF_000146605.3) 8 NC_015018.2 (17021771..17045644, complement)
Build 1.1 previous assembly Turkey_2.01 (GCF_000146605.1) 8 NC_015018.1 (19782400..19806111, complement)

Chromosome 8 - NC_015018.2Genomic Context describing neighboring genes Neighboring gene cytochrome P450 2H1-like Neighboring gene uncharacterized LOC104911956 Neighboring gene membrane associated ring-CH-type finger 8 Neighboring gene zinc finger AN1-type containing 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables arachidonate 5-lipoxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in linoleic acid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipid oxidation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nuclear envelope IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
arachidonate 5-lipoxygenase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Meleagris gallopavo Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Turkey_5.1 Primary Assembly

Genomic

  1. NC_015018.2 Reference Turkey_5.1 Primary Assembly

    Range
    17021771..17045644 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003207969.4 → XP_003208017.1  arachidonate 5-lipoxygenase

    UniProtKB/TrEMBL
    G1N6U6
    Related
    ENSMGAP00000007854.3, ENSMGAT00000008637.3
    Conserved Domains (2) summary
    cd01753
    Location:2 → 115
    PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...
    pfam00305
    Location:227 → 665
    Lipoxygenase
Nucleotide Protein
Heading Accession and Version

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