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themis2 thymocyte selection associated family member 2 [ Danio rerio (zebrafish) ]

Gene ID: 100535600, updated on 2-Nov-2024

Summary

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Official Symbol
themis2provided by ZNC
Official Full Name
thymocyte selection associated family member 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-110411-89
See related
Ensembl:ENSDARG00000058964 AllianceGenome:ZFIN:ZDB-GENE-110411-89
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:ch1073-55d10.2
Summary
Predicted to be involved in T cell receptor signaling pathway. Predicted to be active in cytoplasm and nucleus. Orthologous to human THEMIS2 (thymocyte selection associated family member 2). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See themis2 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (4725643..4749693)
105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (4896233..4917271)

Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene mitochondrial trans-2-enoyl-CoA reductase Neighboring gene sphingomyelin phosphodiesterase acid like 3B Neighboring gene replication protein A2 Neighboring gene ubiquitin protein ligase E3D Neighboring gene trophoblast glycoprotein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Contrasted innate responses to two viruses in zebrafish: insights into the ancestral repertoire of vertebrate IFN-stimulated genes. Briolat V, et al. J Immunol, 2014 May 1. PMID 24683187
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
involved_in T cell receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
protein THEMIS2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007127.7 Reference GRCz11 Primary Assembly

    Range
    4725643..4749693
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021466810.2 → XP_021322485.1  protein THEMIS2 isoform X1

    UniProtKB/TrEMBL
    A0A8M9PMR5, F1QWG7
    Related
    ENSDARP00000076379.5, ENSDART00000081941.5
    Conserved Domains (1) summary
    pfam12736
    Location:19 → 243
    CABIT; Cell-cycle sustaining, positive selection,

  2. XM_005157857.5 → XP_005157914.1  protein THEMIS2 isoform X3

    UniProtKB/TrEMBL
    A0A8M2B454
    Conserved Domains (1) summary
    pfam12736
    Location:19 → 243
    CABIT; Cell-cycle sustaining, positive selection,

  3. XM_021466811.2 → XP_021322486.1  protein THEMIS2 isoform X2

    UniProtKB/TrEMBL
    A0A8M9PJS7
    Related
    ENSDARP00000145030.1, ENSDART00000193513.1
    Conserved Domains (1) summary
    pfam12736
    Location:19 → 243
    CABIT; Cell-cycle sustaining, positive selection,

  4. XM_068214070.1 → XP_068070171.1  protein THEMIS2 isoform X4

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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