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INMT-MINDY4 INMT-MINDY4 readthrough (NMD candidate) [ Homo sapiens (human) ]

Gene ID: 100526825, updated on 10-Oct-2023

Summary

Official Symbol
INMT-MINDY4provided by HGNC
Official Full Name
INMT-MINDY4 readthrough (NMD candidate)provided by HGNC
Primary source
HGNC:HGNC:41995
See related
Ensembl:ENSG00000254959 AllianceGenome:HGNC:41995
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
INMT-FAM188B
Summary
This locus represents rare but naturally occurring read-through transcription between the INMT (indolethylamine N-methyltransferase) and FAM188B (family with sequence similarity 188, member B) genes on chromosome 7. The read-through transcript is unlikely to produce a protein because it is a nonsense-mediated mRNA decay (NMD) candidate based on translation from the supported INMT start codon. [provided by RefSeq, Nov 2010]
Expression
Broad expression in lung (RPKM 13.3), testis (RPKM 8.4) and 24 other tissues See more
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Genomic context

Location:
7p14.3
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (30752135..30892387)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (30889798..31030035)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (30791751..30932002)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124901608 Neighboring gene corticotropin releasing hormone receptor 2 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:30727952-30728462 Neighboring gene uncharacterized LOC105375220 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:30747055-30747555 Neighboring gene uncharacterized LOC105375219 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:30766987-30767488 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18071 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18072 Neighboring gene Sharpr-MPRA regulatory region 4 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18073 Neighboring gene H3K27ac hESC enhancer GRCh37_chr7:30823626-30824126 Neighboring gene indolethylamine N-methyltransferase Neighboring gene MINDY lysine 48 deubiquitinase 4 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25817 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25818 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25819 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:30893171-30894073 Neighboring gene ReSE screen-validated silencer GRCh37_chr7:30901315-30901474 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:30923659-30924560 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:30941843-30942646 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:30942647-30943449 Neighboring gene oxysterol binding protein like 9 pseudogene 6 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:30946833-30947332 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:30948457-30948956 Neighboring gene ReSE screen-validated silencer GRCh37_chr7:30961348-30961528 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25820 Neighboring gene aquaporin 1 (Colton blood group) Neighboring gene ReSE screen-validated silencer GRCh37_chr7:31014486-31014664 Neighboring gene growth hormone releasing hormone receptor

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Other Names

  • INMT-FAM188B readthrough (NMD candidate)
  • INMT-FAM188B readthrough (non-protein coding)

Clone Names

  • FLJ98803

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_037598.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC004691, AC006022, AK308762
    Related
    ENST00000458257.5

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

    Range
    30752135..30892387
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060931.1 Alternate T2T-CHM13v2.0

    Range
    30889798..31030035
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)