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DDX50 DExD-box helicase 50 [ Sus scrofa (pig) ]

Gene ID: 100519874, updated on 17-Aug-2024

Summary

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Official Symbol
DDX50provided by VGNC
Official Full Name
DExD-box helicase 50provided by VGNC
Primary source
VGNC:VGNC:87227
See related
Ensembl:ENSSSCG00000010246
Gene type
protein coding
RefSeq status
MODEL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression
Ubiquitous expression in ovary (RPKM 13.1), spleen (RPKM 11.9) and 8 other tissues See more
Orthologs
human mouse all
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Genomic context

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See DDX50 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
16
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 14 NC_010456.5 (71989137..72030996)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 14 NC_010456.4 (78004480..78045914)

Chromosome 14 - NC_010456.5Genomic Context describing neighboring genes Neighboring gene cell division cycle and apoptosis regulator 1 Neighboring gene uncharacterized LOC106508088 Neighboring gene storkhead box 1 Neighboring gene uncharacterized LOC106508089 Neighboring gene DExD-box helicase 21 Neighboring gene kinesin family binding protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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Related articles in PubMed

  1. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
  2. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA helicase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ATP-dependent RNA helicase DDX50
Names
DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
DEAD-box helicase 50

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010456.5 Reference Sscrofa11.1 Primary Assembly

    Range
    71989137..72030996
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005657388.3 → XP_005657445.1  ATP-dependent RNA helicase DDX50 isoform X1

    UniProtKB/TrEMBL
    A0A480TWK4
    Conserved Domains (4) summary
    COG0513
    Location:139 → 630
    SrmB; Superfamily II DNA and RNA helicase [Replication, recombination and repair]
    cd00079
    Location:391 → 508
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
    cd00268
    Location:158 → 361
    DEADc; DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif ...
    cd12936
    Location:587 → 678
    GUCT_RHII_Gualpha_beta; RNA-binding GUCT domain found in vertebrate RNA helicase II/Gualpha (RH-II/Gualpha), RNA helicase II/Gubeta (RH-II/Gubeta) and similar proteins

  2. XM_005657389.3 → XP_005657446.1  ATP-dependent RNA helicase DDX50 isoform X3

    UniProtKB/TrEMBL
    A0A480TWK4
    Conserved Domains (4) summary
    COG0513
    Location:139 → 576
    SrmB; Superfamily II DNA and RNA helicase [Replication, recombination and repair]
    cd00268
    Location:158 → 361
    DEADc; DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif ...
    cd12936
    Location:533 → 624
    GUCT_RHII_Gualpha_beta; RNA-binding GUCT domain found in vertebrate RNA helicase II/Gualpha (RH-II/Gualpha), RNA helicase II/Gubeta (RH-II/Gubeta) and similar proteins
    cl21455
    Location:308 → 454
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  3. XM_003133052.5 → XP_003133100.1  ATP-dependent RNA helicase DDX50 isoform X2

    UniProtKB/TrEMBL
    A0A480TWK4, A0A481C1W3, A0A4X1TLH4, A0A8D0NQ41
    Related
    ENSSSCP00000010924.5, ENSSSCT00000011216.5
    Conserved Domains (4) summary
    COG0513
    Location:121 → 612
    SrmB; Superfamily II DNA and RNA helicase [Replication, recombination and repair]
    cd00079
    Location:373 → 490
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
    cd00268
    Location:140 → 343
    DEADc; DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif ...
    cd12936
    Location:569 → 660
    GUCT_RHII_Gualpha_beta; RNA-binding GUCT domain found in vertebrate RNA helicase II/Gualpha (RH-II/Gualpha), RNA helicase II/Gubeta (RH-II/Gubeta) and similar proteins

  4. XM_021072504.1 → XP_020928163.1  ATP-dependent RNA helicase DDX50 isoform X4

    UniProtKB/TrEMBL
    A0A480TWK4, A0A8D0V311, A0A8D1ZYE2
    Conserved Domains (2) summary
    COG0513
    Location:121 → 558
    SrmB; Superfamily II DNA and RNA helicase [Replication, recombination and repair]
    cd12936
    Location:515 → 606
    GUCT_RHII_Gualpha_beta; RNA-binding GUCT domain found in vertebrate RNA helicase II/Gualpha (RH-II/Gualpha), RNA helicase II/Gubeta (RH-II/Gubeta) and similar proteins
Nucleotide Protein
Heading Accession and Version

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