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SPHK1 sphingosine kinase 1 [ Sus scrofa (pig) ]

Gene ID: 100519210, updated on 17-Aug-2024

Summary

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Official Symbol
SPHK1provided by VGNC
Official Full Name
sphingosine kinase 1provided by VGNC
Primary source
VGNC:VGNC:93404
See related
Ensembl:ENSSSCG00000017178
Gene type
protein coding
RefSeq status
MODEL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression
Biased expression in ovary (RPKM 16.4), spleen (RPKM 4.6) and 4 other tissues See more
Orthologs
human mouse all
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Genomic context

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See SPHK1 in Genome Data Viewer
Location:
chromosome: 12
Exon count:
9
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 12 NC_010454.4 (5114946..5122580, complement)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 12 NC_010454.3 (5018690..5023812, complement)

Chromosome 12 - NC_010454.4Genomic Context describing neighboring genes Neighboring gene serotonin N-acetyltransferase Neighboring gene ubiquitin conjugating enzyme E2 O Neighboring gene uncharacterized LOC110255966 Neighboring gene phosphoribosyl pyrophosphate synthetase associated protein 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables D-erythro-sphingosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to growth factor stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sphingosine biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in intracellular membrane-bounded organelle IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
sphingosine kinase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010454.4 Reference Sscrofa11.1 Primary Assembly

    Range
    5114946..5122580 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021066591.1 → XP_020922250.1  sphingosine kinase 1 isoform X3

    UniProtKB/TrEMBL
    A0A8D0I7N8
    Conserved Domains (1) summary
    cl27661
    Location:11 → 348
    LCB5; Diacylglycerol kinase family enzyme [Lipid transport and metabolism, General function prediction only]

  2. XM_021066590.1 → XP_020922249.1  sphingosine kinase 1 isoform X3

    UniProtKB/TrEMBL
    A0A8D0I7N8
    Conserved Domains (1) summary
    cl27661
    Location:11 → 348
    LCB5; Diacylglycerol kinase family enzyme [Lipid transport and metabolism, General function prediction only]

  3. XM_005656916.3 → XP_005656973.1  sphingosine kinase 1 isoform X2

    UniProtKB/TrEMBL
    A0A4X1UUU4, A0A8D1PZF5, F1RWP6
    Related
    ENSSSCP00000018202.3, ENSSSCT00000018703.5
    Conserved Domains (2) summary
    PLN02958
    Location:97 → 434
    PLN02958; diacylglycerol kinase/D-erythro-sphingosine kinase
    pfam00781
    Location:102 → 241
    DAGK_cat; Diacylglycerol kinase catalytic domain

  4. XM_005656918.3 → XP_005656975.1  sphingosine kinase 1 isoform X3

    See identical proteins and their annotated locations for XP_005656975.1

    UniProtKB/TrEMBL
    A0A8D0I7N8
    Conserved Domains (1) summary
    cl27661
    Location:11 → 348
    LCB5; Diacylglycerol kinase family enzyme [Lipid transport and metabolism, General function prediction only]

  5. XM_021066593.1 → XP_020922252.1  sphingosine kinase 1 isoform X3

    UniProtKB/TrEMBL
    A0A8D0I7N8
    Conserved Domains (1) summary
    cl27661
    Location:11 → 348
    LCB5; Diacylglycerol kinase family enzyme [Lipid transport and metabolism, General function prediction only]

  6. XM_005656915.3 → XP_005656972.1  sphingosine kinase 1 isoform X1

    UniProtKB/TrEMBL
    A0A287AP24, A0A8D0V8B2
    Conserved Domains (2) summary
    PLN02958
    Location:111 → 448
    PLN02958; diacylglycerol kinase/D-erythro-sphingosine kinase
    pfam00781
    Location:116 → 255
    DAGK_cat; Diacylglycerol kinase catalytic domain

  7. XM_021066589.1 → XP_020922248.1  sphingosine kinase 1 isoform X3

    UniProtKB/TrEMBL
    A0A8D0I7N8
    Conserved Domains (1) summary
    cl27661
    Location:11 → 348
    LCB5; Diacylglycerol kinase family enzyme [Lipid transport and metabolism, General function prediction only]

  8. XM_021066592.1 → XP_020922251.1  sphingosine kinase 1 isoform X3

    UniProtKB/TrEMBL
    A0A8D0I7N8
    Conserved Domains (1) summary
    cl27661
    Location:11 → 348
    LCB5; Diacylglycerol kinase family enzyme [Lipid transport and metabolism, General function prediction only]
Nucleotide Protein
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