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HSPG2 heparan sulfate proteoglycan 2 [ Sus scrofa (pig) ]

Gene ID: 100517288, updated on 17-Aug-2024

Summary

Official Symbol
HSPG2provided by VGNC
Official Full Name
heparan sulfate proteoglycan 2provided by VGNC
Primary source
VGNC:VGNC:97099
See related
Ensembl:ENSSSCG00000003514
Gene type
protein coding
RefSeq status
MODEL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression
Ubiquitous expression in subcutaneous adipose (RPKM 77.5), heart (RPKM 51.4) and 8 other tissues See more
Orthologs
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Genomic context

See HSPG2 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
103
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 6 NC_010448.4 (79849691..79958283, complement)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 6 NC_010448.3 (73882694..73947389)

Chromosome 6 - NC_010448.4Genomic Context describing neighboring genes Neighboring gene ubiquitin specific peptidase 48 Neighboring gene uncharacterized LOC110261110 Neighboring gene low density lipoprotein receptor class A domain containing 2 Neighboring gene uncharacterized LOC100517477 Neighboring gene proproteinase E

Genomic regions, transcripts, and products

Expression

  • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables cell adhesion molecule binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cell-cell junction IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
basement membrane-specific heparan sulfate proteoglycan core protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010448.4 Reference Sscrofa11.1 Primary Assembly

    Range
    79849691..79958283 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021095485.1XP_020951144.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X6

    UniProtKB/TrEMBL
    A0A286ZHV7
    Conserved Domains (18) summary
    cd05743
    Location:424501
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan, also known as HSPG2, and similar domains
    cd05754
    Location:19152000
    Ig_Perlecan_like; Igmmunoglobulin (Ig)-like domain found in Perlecan and similar proteins
    smart00180
    Location:17571805
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00200
    Location:80194
    SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
    smart00281
    Location:593719
    LamB; Laminin B domain
    smart00409
    Location:27892866
    IG; Immunoglobulin
    smart00410
    Location:25962673
    IG_like; Immunoglobulin like
    cd00054
    Location:43034334
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:11611210
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:43614520
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:288322
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    pfam07679
    Location:21002186
    I-set; Immunoglobulin I-set domain
    pfam00053
    Location:12791326
    Laminin_EGF; Laminin EGF domain
    pfam00008
    Location:42664296
    EGF; EGF-like domain
    pfam00052
    Location:9931127
    Laminin_B; Laminin B (Domain IV)
    pfam13927
    Location:33643433
    Ig_3; Immunoglobulin domain
    cl11960
    Location:35693635
    Ig; Immunoglobulin domain
    cl28434
    Location:34513534
    I-set; Immunoglobulin I-set domain
  2. XM_021095484.1XP_020951143.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X5

    UniProtKB/TrEMBL
    A0A286ZHV7
    Conserved Domains (18) summary
    cd05743
    Location:424501
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan, also known as HSPG2, and similar domains
    cd05754
    Location:19222007
    Ig_Perlecan_like; Igmmunoglobulin (Ig)-like domain found in Perlecan and similar proteins
    smart00180
    Location:17641812
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00200
    Location:80194
    SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
    smart00281
    Location:593719
    LamB; Laminin B domain
    smart00409
    Location:18341914
    IG; Immunoglobulin
    smart00410
    Location:27962873
    IG_like; Immunoglobulin like
    cd00054
    Location:43104341
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:11681217
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:43684527
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:288322
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    pfam07679
    Location:21072193
    I-set; Immunoglobulin I-set domain
    pfam00053
    Location:12861333
    Laminin_EGF; Laminin EGF domain
    pfam00008
    Location:42734303
    EGF; EGF-like domain
    pfam00052
    Location:10001134
    Laminin_B; Laminin B (Domain IV)
    pfam13927
    Location:33713440
    Ig_3; Immunoglobulin domain
    cl11960
    Location:35763642
    Ig; Immunoglobulin domain
    cl28434
    Location:34583541
    I-set; Immunoglobulin I-set domain
  3. XM_021095483.1XP_020951142.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X4

    UniProtKB/TrEMBL
    A0A286ZHV7
    Conserved Domains (18) summary
    cd05743
    Location:441518
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan, also known as HSPG2, and similar domains
    cd05754
    Location:19322017
    Ig_Perlecan_like; Igmmunoglobulin (Ig)-like domain found in Perlecan and similar proteins
    smart00180
    Location:17741822
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00200
    Location:80193
    SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
    smart00281
    Location:610736
    LamB; Laminin B domain
    smart00409
    Location:28062883
    IG; Immunoglobulin
    smart00410
    Location:26132690
    IG_like; Immunoglobulin like
    cd00054
    Location:43204351
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:11781227
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:43784537
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:305339
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    pfam07679
    Location:21172203
    I-set; Immunoglobulin I-set domain
    pfam00053
    Location:12961343
    Laminin_EGF; Laminin EGF domain
    pfam00008
    Location:42834313
    EGF; EGF-like domain
    pfam00052
    Location:10101144
    Laminin_B; Laminin B (Domain IV)
    pfam13927
    Location:33813450
    Ig_3; Immunoglobulin domain
    cl11960
    Location:35863652
    Ig; Immunoglobulin domain
    cl28434
    Location:34683551
    I-set; Immunoglobulin I-set domain
  4. XM_021095486.1XP_020951145.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X7

    UniProtKB/TrEMBL
    A0A286ZHV7
    Conserved Domains (18) summary
    cd05743
    Location:441518
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan, also known as HSPG2, and similar domains
    cd05754
    Location:19051990
    Ig_Perlecan_like; Igmmunoglobulin (Ig)-like domain found in Perlecan and similar proteins
    smart00180
    Location:17471795
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00200
    Location:80193
    SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
    smart00281
    Location:610736
    LamB; Laminin B domain
    smart00409
    Location:25862663
    IG; Immunoglobulin
    smart00410
    Location:27792856
    IG_like; Immunoglobulin like
    cd00054
    Location:42934324
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:11851234
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:43514510
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:305339
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    pfam07679
    Location:20902176
    I-set; Immunoglobulin I-set domain
    pfam00053
    Location:13031350
    Laminin_EGF; Laminin EGF domain
    pfam00008
    Location:42564286
    EGF; EGF-like domain
    pfam00052
    Location:10171151
    Laminin_B; Laminin B (Domain IV)
    pfam13927
    Location:33543423
    Ig_3; Immunoglobulin domain
    cl11960
    Location:35593625
    Ig; Immunoglobulin domain
    cl28434
    Location:34413524
    I-set; Immunoglobulin I-set domain
  5. XM_021095481.1XP_020951140.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X2

    UniProtKB/TrEMBL
    A0A286ZHV7
    Conserved Domains (18) summary
    cd05743
    Location:441518
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan, also known as HSPG2, and similar domains
    cd05754
    Location:19382023
    Ig_Perlecan_like; Igmmunoglobulin (Ig)-like domain found in Perlecan and similar proteins
    smart00180
    Location:17811829
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00200
    Location:80193
    SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
    smart00281
    Location:610736
    LamB; Laminin B domain
    smart00409
    Location:26192696
    IG; Immunoglobulin
    smart00410
    Location:28122889
    IG_like; Immunoglobulin like
    cd00054
    Location:43264357
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:11851234
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:43844543
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:305339
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    pfam07679
    Location:21232209
    I-set; Immunoglobulin I-set domain
    pfam00053
    Location:13031350
    Laminin_EGF; Laminin EGF domain
    pfam00008
    Location:42894319
    EGF; EGF-like domain
    pfam00052
    Location:10171151
    Laminin_B; Laminin B (Domain IV)
    pfam13927
    Location:33873456
    Ig_3; Immunoglobulin domain
    cl11960
    Location:35923658
    Ig; Immunoglobulin domain
    cl28434
    Location:34743557
    I-set; Immunoglobulin I-set domain
  6. XM_021095494.1XP_020951153.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X15

    UniProtKB/TrEMBL
    A0A8D1S8S8
    Conserved Domains (18) summary
    cd05743
    Location:441518
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan, also known as HSPG2, and similar domains
    cd05754
    Location:19392024
    Ig_Perlecan_like; Igmmunoglobulin (Ig)-like domain found in Perlecan and similar proteins
    smart00180
    Location:17811829
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00200
    Location:80193
    SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
    smart00281
    Location:610736
    LamB; Laminin B domain
    smart00409
    Location:23312408
    IG; Immunoglobulin
    smart00410
    Location:25242601
    IG_like; Immunoglobulin like
    cd00054
    Location:40384069
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:11851234
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:40964255
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:305339
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    pfam07679
    Location:21242210
    I-set; Immunoglobulin I-set domain
    pfam00053
    Location:13031350
    Laminin_EGF; Laminin EGF domain
    pfam00008
    Location:40014031
    EGF; EGF-like domain
    pfam00052
    Location:10171151
    Laminin_B; Laminin B (Domain IV)
    pfam13927
    Location:30993168
    Ig_3; Immunoglobulin domain
    cl11960
    Location:33043370
    Ig; Immunoglobulin domain
    cl28434
    Location:31863269
    I-set; Immunoglobulin I-set domain
  7. XM_021095488.1XP_020951147.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X9

    UniProtKB/TrEMBL
    A0A8D1S375
    Conserved Domains (18) summary
    cd05743
    Location:441518
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan, also known as HSPG2, and similar domains
    cd05754
    Location:19392024
    Ig_Perlecan_like; Igmmunoglobulin (Ig)-like domain found in Perlecan and similar proteins
    smart00180
    Location:17811829
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00200
    Location:80193
    SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
    smart00281
    Location:610736
    LamB; Laminin B domain
    smart00409
    Location:27152792
    IG; Immunoglobulin
    smart00410
    Location:22262303
    IG_like; Immunoglobulin like
    cd00054
    Location:42294260
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:11851234
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:42874446
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:305339
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    pfam07679
    Location:21242210
    I-set; Immunoglobulin I-set domain
    pfam00053
    Location:13031350
    Laminin_EGF; Laminin EGF domain
    pfam00008
    Location:41924222
    EGF; EGF-like domain
    pfam00052
    Location:10171151
    Laminin_B; Laminin B (Domain IV)
    pfam13927
    Location:32903359
    Ig_3; Immunoglobulin domain
    cl11960
    Location:34953561
    Ig; Immunoglobulin domain
    cl28434
    Location:33773460
    I-set; Immunoglobulin I-set domain
  8. XM_021095487.1XP_020951146.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X8

    UniProtKB/TrEMBL
    A0A286ZHV7
    Conserved Domains (18) summary
    cd05743
    Location:441518
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan, also known as HSPG2, and similar domains
    cd05754
    Location:19392024
    Ig_Perlecan_like; Igmmunoglobulin (Ig)-like domain found in Perlecan and similar proteins
    smart00180
    Location:17811829
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00200
    Location:80193
    SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
    smart00281
    Location:610736
    LamB; Laminin B domain
    smart00409
    Location:27172794
    IG; Immunoglobulin
    smart00410
    Location:25242601
    IG_like; Immunoglobulin like
    cd00054
    Location:42314262
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:11851234
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:42894448
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:305339
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    pfam07679
    Location:21242210
    I-set; Immunoglobulin I-set domain
    pfam00053
    Location:13031350
    Laminin_EGF; Laminin EGF domain
    pfam00008
    Location:41944224
    EGF; EGF-like domain
    pfam00052
    Location:10171151
    Laminin_B; Laminin B (Domain IV)
    pfam13927
    Location:32923361
    Ig_3; Immunoglobulin domain
    cl11960
    Location:34973563
    Ig; Immunoglobulin domain
    cl28434
    Location:33793462
    I-set; Immunoglobulin I-set domain
  9. XM_021095493.1XP_020951152.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X14

    UniProtKB/TrEMBL
    A0A286ZHV7, A0A480WWH8, A0A481BCW8
    Conserved Domains (18) summary
    cd05743
    Location:441518
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan, also known as HSPG2, and similar domains
    cd05754
    Location:19392024
    Ig_Perlecan_like; Igmmunoglobulin (Ig)-like domain found in Perlecan and similar proteins
    smart00180
    Location:17811829
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00200
    Location:80193
    SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
    smart00281
    Location:610736
    LamB; Laminin B domain
    smart00409
    Location:26202697
    IG; Immunoglobulin
    smart00410
    Location:23312408
    IG_like; Immunoglobulin like
    cd00054
    Location:41244155
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:11851234
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:41824341
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:305339
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    pfam07679
    Location:28072890
    I-set; Immunoglobulin I-set domain
    pfam00053
    Location:13031350
    Laminin_EGF; Laminin EGF domain
    pfam00008
    Location:40874117
    EGF; EGF-like domain
    pfam00052
    Location:10171151
    Laminin_B; Laminin B (Domain IV)
    pfam13927
    Location:31913260
    Ig_3; Immunoglobulin domain
    cl11960
    Location:33963462
    Ig; Immunoglobulin domain
    cl28434
    Location:32783361
    I-set; Immunoglobulin I-set domain
  10. XM_021095492.1XP_020951151.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X13

    UniProtKB/TrEMBL
    A0A286ZHV7, A0A480WWH8, A0A481BCW8
    Conserved Domains (18) summary
    cd05743
    Location:441518
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan, also known as HSPG2, and similar domains
    cd05754
    Location:19392024
    Ig_Perlecan_like; Igmmunoglobulin (Ig)-like domain found in Perlecan and similar proteins
    smart00180
    Location:17811829
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00200
    Location:80193
    SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
    smart00281
    Location:610736
    LamB; Laminin B domain
    smart00409
    Location:26202697
    IG; Immunoglobulin
    smart00410
    Location:23312408
    IG_like; Immunoglobulin like
    cd00054
    Location:41304161
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:11851234
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:41884347
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:305339
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    pfam07679
    Location:28072890
    I-set; Immunoglobulin I-set domain
    pfam00053
    Location:13031350
    Laminin_EGF; Laminin EGF domain
    pfam00008
    Location:40934123
    EGF; EGF-like domain
    pfam00052
    Location:10171151
    Laminin_B; Laminin B (Domain IV)
    pfam13927
    Location:31913260
    Ig_3; Immunoglobulin domain
    cl11960
    Location:33963462
    Ig; Immunoglobulin domain
    cl28434
    Location:32783361
    I-set; Immunoglobulin I-set domain
  11. XM_021095482.1XP_020951141.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X3

    UniProtKB/TrEMBL
    A0A286ZHV7
    Conserved Domains (18) summary
    cd05743
    Location:441518
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan, also known as HSPG2, and similar domains
    cd05754
    Location:19392024
    Ig_Perlecan_like; Igmmunoglobulin (Ig)-like domain found in Perlecan and similar proteins
    smart00180
    Location:17811829
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00200
    Location:80193
    SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
    smart00281
    Location:610736
    LamB; Laminin B domain
    smart00409
    Location:26202697
    IG; Immunoglobulin
    smart00410
    Location:28132890
    IG_like; Immunoglobulin like
    cd00054
    Location:43214352
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:11851234
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:43794538
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:305339
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    pfam07679
    Location:21242210
    I-set; Immunoglobulin I-set domain
    pfam00053
    Location:13031350
    Laminin_EGF; Laminin EGF domain
    pfam00008
    Location:42844314
    EGF; EGF-like domain
    pfam00052
    Location:10171151
    Laminin_B; Laminin B (Domain IV)
    pfam13927
    Location:33883457
    Ig_3; Immunoglobulin domain
    cl11960
    Location:35933659
    Ig; Immunoglobulin domain
    cl28434
    Location:34753558
    I-set; Immunoglobulin I-set domain
  12. XM_021095480.1XP_020951139.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X1

    UniProtKB/TrEMBL
    A0A286ZHV7
    Conserved Domains (18) summary
    cd05743
    Location:441518
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan, also known as HSPG2, and similar domains
    cd05754
    Location:19392024
    Ig_Perlecan_like; Igmmunoglobulin (Ig)-like domain found in Perlecan and similar proteins
    smart00180
    Location:17811829
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00200
    Location:80193
    SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
    smart00281
    Location:610736
    LamB; Laminin B domain
    smart00409
    Location:26202697
    IG; Immunoglobulin
    smart00410
    Location:28132890
    IG_like; Immunoglobulin like
    cd00054
    Location:43274358
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:11851234
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:43854544
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:305339
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    pfam07679
    Location:21242210
    I-set; Immunoglobulin I-set domain
    pfam00053
    Location:13031350
    Laminin_EGF; Laminin EGF domain
    pfam00008
    Location:42904320
    EGF; EGF-like domain
    pfam00052
    Location:10171151
    Laminin_B; Laminin B (Domain IV)
    pfam13927
    Location:33883457
    Ig_3; Immunoglobulin domain
    cl11960
    Location:35933659
    Ig; Immunoglobulin domain
    cl28434
    Location:34753558
    I-set; Immunoglobulin I-set domain
  13. XM_021095496.1XP_020951155.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X17

    UniProtKB/TrEMBL
    A0A286ZHV7
    Conserved Domains (18) summary
    cd05743
    Location:424501
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan, also known as HSPG2, and similar domains
    cd05754
    Location:17741859
    Ig_Perlecan_like; Igmmunoglobulin (Ig)-like domain found in Perlecan and similar proteins
    smart00180
    Location:16171665
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00200
    Location:80194
    SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
    smart00281
    Location:13951520
    LamB; Laminin B domain
    smart00409
    Location:26482725
    IG; Immunoglobulin
    smart00410
    Location:28462922
    IG_like; Immunoglobulin like
    cd00054
    Location:41564187
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:11611210
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:42144373
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:288322
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    pfam07679
    Location:19592045
    I-set; Immunoglobulin I-set domain
    pfam00053
    Location:12791326
    Laminin_EGF; Laminin EGF domain
    pfam00008
    Location:41194149
    EGF; EGF-like domain
    pfam00052
    Location:9931127
    Laminin_B; Laminin B (Domain IV)
    pfam13927
    Location:32233292
    Ig_3; Immunoglobulin domain
    cl11960
    Location:34283494
    Ig; Immunoglobulin domain
    cl28434
    Location:33103393
    I-set; Immunoglobulin I-set domain
  14. XM_021095495.1XP_020951154.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X16

    UniProtKB/TrEMBL
    A0A286ZHV7
    Related
    ENSSSCP00000031125.2, ENSSSCT00000064564.3
    Conserved Domains (18) summary
    cd05743
    Location:424501
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan, also known as HSPG2, and similar domains
    cd05754
    Location:17751860
    Ig_Perlecan_like; Igmmunoglobulin (Ig)-like domain found in Perlecan and similar proteins
    smart00180
    Location:16171665
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00200
    Location:80194
    SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
    smart00281
    Location:13951520
    LamB; Laminin B domain
    smart00409
    Location:26492726
    IG; Immunoglobulin
    smart00410
    Location:28472923
    IG_like; Immunoglobulin like
    cd00054
    Location:41574188
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:11611210
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:42154374
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:288322
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    pfam07679
    Location:19602046
    I-set; Immunoglobulin I-set domain
    pfam00053
    Location:12791326
    Laminin_EGF; Laminin EGF domain
    pfam00008
    Location:41204150
    EGF; EGF-like domain
    pfam00052
    Location:9931127
    Laminin_B; Laminin B (Domain IV)
    pfam13927
    Location:32243293
    Ig_3; Immunoglobulin domain
    cl11960
    Location:34293495
    Ig; Immunoglobulin domain
    cl28434
    Location:33113394
    I-set; Immunoglobulin I-set domain
  15. XM_021095491.1XP_020951150.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X12

    UniProtKB/TrEMBL
    A0A286ZHV7
    Conserved Domains (18) summary
    cd05743
    Location:424501
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan, also known as HSPG2, and similar domains
    cd05754
    Location:17751860
    Ig_Perlecan_like; Igmmunoglobulin (Ig)-like domain found in Perlecan and similar proteins
    smart00180
    Location:16171665
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00200
    Location:80194
    SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
    smart00281
    Location:13951520
    LamB; Laminin B domain
    smart00409
    Location:24562533
    IG; Immunoglobulin
    smart00410
    Location:26492726
    IG_like; Immunoglobulin like
    cd00054
    Location:41634194
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:11611210
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:42214380
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:288322
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    pfam07679
    Location:19602046
    I-set; Immunoglobulin I-set domain
    pfam00053
    Location:12791326
    Laminin_EGF; Laminin EGF domain
    pfam00008
    Location:41264156
    EGF; EGF-like domain
    pfam00052
    Location:9931127
    Laminin_B; Laminin B (Domain IV)
    pfam13927
    Location:32243293
    Ig_3; Immunoglobulin domain
    cl11960
    Location:34293495
    Ig; Immunoglobulin domain
    cl28434
    Location:33113394
    I-set; Immunoglobulin I-set domain
  16. XM_021095490.1XP_020951149.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X11

    UniProtKB/TrEMBL
    A0A286ZHV7
    Conserved Domains (18) summary
    cd05743
    Location:441518
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan, also known as HSPG2, and similar domains
    cd05754
    Location:17981883
    Ig_Perlecan_like; Igmmunoglobulin (Ig)-like domain found in Perlecan and similar proteins
    smart00180
    Location:16411689
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00200
    Location:80193
    SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
    smart00281
    Location:14191544
    LamB; Laminin B domain
    smart00409
    Location:20852162
    IG; Immunoglobulin
    smart00410
    Location:26722749
    IG_like; Immunoglobulin like
    cd00054
    Location:41864217
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:11851234
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:42444403
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:305339
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    pfam07679
    Location:19832069
    I-set; Immunoglobulin I-set domain
    pfam00053
    Location:13031350
    Laminin_EGF; Laminin EGF domain
    pfam00008
    Location:41494179
    EGF; EGF-like domain
    pfam00052
    Location:10171151
    Laminin_B; Laminin B (Domain IV)
    pfam13927
    Location:32473316
    Ig_3; Immunoglobulin domain
    cl11960
    Location:34523518
    Ig; Immunoglobulin domain
    cl28434
    Location:33343417
    I-set; Immunoglobulin I-set domain
  17. XM_021095489.1XP_020951148.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X10

    UniProtKB/TrEMBL
    A0A286ZHV7
    Conserved Domains (18) summary
    cd05743
    Location:441518
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan, also known as HSPG2, and similar domains
    cd05754
    Location:17991884
    Ig_Perlecan_like; Igmmunoglobulin (Ig)-like domain found in Perlecan and similar proteins
    smart00180
    Location:16411689
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00200
    Location:80193
    SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
    smart00281
    Location:14191544
    LamB; Laminin B domain
    smart00409
    Location:20862163
    IG; Immunoglobulin
    smart00410
    Location:26732750
    IG_like; Immunoglobulin like
    cd00054
    Location:41874218
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:11851234
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:42454404
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:305339
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    pfam07679
    Location:19842070
    I-set; Immunoglobulin I-set domain
    pfam00053
    Location:13031350
    Laminin_EGF; Laminin EGF domain
    pfam00008
    Location:41504180
    EGF; EGF-like domain
    pfam00052
    Location:10171151
    Laminin_B; Laminin B (Domain IV)
    pfam13927
    Location:32483317
    Ig_3; Immunoglobulin domain
    cl11960
    Location:34533519
    Ig; Immunoglobulin domain
    cl28434
    Location:33353418
    I-set; Immunoglobulin I-set domain