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PLPP1 phospholipid phosphatase 1 [ Sus scrofa (pig) ]

Gene ID: 100515451, updated on 17-Aug-2024

Summary

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Official Symbol
PLPP1provided by VGNC
Official Full Name
phospholipid phosphatase 1provided by VGNC
Primary source
VGNC:VGNC:91570
See related
Ensembl:ENSSSCG00000016912
Gene type
protein coding
RefSeq status
MODEL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Also known as
LPP1; PAP2a; PAP-2a; PPAP2A; PAP2-alpha
Expression
Ubiquitous expression in lung (RPKM 72.2), subcutaneous adipose (RPKM 71.2) and 8 other tissues See more
Orthologs
human mouse all
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Genomic context

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See PLPP1 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
9
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 16 NC_010458.4 (34604367..34741524, complement)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 16 NC_010458.3 (36713167..36857699, complement)

Chromosome 16 - NC_010458.4Genomic Context describing neighboring genes Neighboring gene 40S ribosomal protein S29 pseudogene Neighboring gene Mtr4 exosome RNA helicase Neighboring gene 60S ribosomal protein L34 pseudogene Neighboring gene solute carrier family 38 member 9 Neighboring gene uncharacterized LOC102165748 Neighboring gene DEAD-box helicase 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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Related articles in PubMed

  1. Purification and properties of phosphatidic acid phosphatase from porcine thymus membranes. Kanoh H, et al. J Biol Chem, 1992 Dec 15. PMID 1334090
  2. Identification and cDNA cloning of 35-kDa phosphatidic acid phosphatase (type 2) bound to plasma membranes. Polymerase chain reaction amplification of mouse H2O2-inducible hic53 clone yielded the cDNA encoding phosphatidic acid phosphatase. Kai M, et al. J Biol Chem, 1996 Aug 2. PMID 8702556
  3. Comparative analysis of protein coding sequences from human, mouse and the domesticated pig. Jørgensen FG, et al. BMC Biol, 2005 Jan 28. PMID 15679890, Free PMC Article
  4. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables phosphatidate phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in phospholipid dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phospholipid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phospholipid phosphatase 1
Names
Lipid phosphate phosphohydrolase 1
Phosphatidate phosphohydrolase type 2a
Phosphatidic acid phosphatase 2a

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010458.4 Reference Sscrofa11.1 Primary Assembly

    Range
    34604367..34741524 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003133951.6 → XP_003133999.3  phospholipid phosphatase 1 isoform X4

    UniProtKB/Swiss-Prot
    A0A286ZIK9, P60588
    UniProtKB/TrEMBL
    A0A4X1SKZ5
    Related
    ENSSSCP00000031391.1, ENSSSCT00000042472.2
    Conserved Domains (1) summary
    cd03384
    Location:98 → 243
    PAP2_wunen; PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the ...

  2. XM_003483822.4 → XP_003483870.1  phospholipid phosphatase 1 isoform X3

    UniProtKB/TrEMBL
    A0A286ZXH9, A0A4X1SM51, A0A8D0IRE7
    Related
    ENSSSCP00000036392.1, ENSSSCT00000057634.2
    Conserved Domains (1) summary
    cd03384
    Location:99 → 244
    PAP2_wunen; PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the ...

  3. XM_013984779.2 → XP_013840233.1  phospholipid phosphatase 1 isoform X5

    UniProtKB/TrEMBL
    A0A4X1SKY6, A0A8D0ILX9, A0A8D0IR45
    Conserved Domains (1) summary
    cd03384
    Location:90 → 235
    PAP2_wunen; PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the ...

  4. XM_013984778.2 → XP_013840232.1  phospholipid phosphatase 1 isoform X2

    UniProtKB/TrEMBL
    A0A4X1SKZ5, A0A4X1SM48
    Conserved Domains (1) summary
    cd03384
    Location:103 → 248
    PAP2_wunen; PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the ...

  5. XM_013984777.2 → XP_013840231.1  phospholipid phosphatase 1 isoform X1

    UniProtKB/TrEMBL
    A0A4X1SL15, A0A8D0IRE7
    Conserved Domains (1) summary
    cd03384
    Location:104 → 249
    PAP2_wunen; PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P60588.2 GenPept UniProtKB/Swiss-Prot:P60588

Gene LinkOut