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UXS1 UDP-glucuronate decarboxylase 1 [ Sus scrofa (pig) ]

Gene ID: 100513145, updated on 17-Aug-2024

Summary

Official Symbol
UXS1provided by VGNC
Official Full Name
UDP-glucuronate decarboxylase 1provided by VGNC
Primary source
VGNC:VGNC:94791
See related
Ensembl:ENSSSCG00000008143
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression
Ubiquitous expression in ovary (RPKM 39.9), heart (RPKM 16.1) and 8 other tissues See more
Orthologs
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Genomic context

See UXS1 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
17
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 3 NC_010445.4 (48871036..48940736)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 3 NC_010445.3 (51082501..51149409, complement)

Chromosome 3 - NC_010445.4Genomic Context describing neighboring genes Neighboring gene translation initiation factor IF-2-like Neighboring gene ST6 beta-galactoside alpha-2,6-sialyltransferase 2 Neighboring gene transfer RNA serine (anticodon AGA) Neighboring gene ECRG4 augurin precursor Neighboring gene uncharacterized LOC106509743 Neighboring gene NCK adaptor protein 2

Genomic regions, transcripts, and products

Expression

  • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables NAD+ binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables UDP-glucuronate decarboxylase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in D-xylose metabolic process IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
UDP-glucuronic acid decarboxylase 1
NP_001231702.1
NP_001231703.1
XP_020941324.1
XP_020941325.1
XP_020941326.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001244773.1NP_001231702.1  UDP-glucuronic acid decarboxylase 1 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
    Source sequence(s)
    AK348570
    UniProtKB/TrEMBL
    A0A480TRQ6, A0A8D1N0E3, F1SU22
    Conserved Domains (3) summary
    cd05230
    Location:94397
    UGD_SDR_e; UDP-glucuronate decarboxylase (UGD) and related proteins, extended (e) SDRs
    COG0451
    Location:94401
    WcaG; Nucleoside-diphosphate-sugar epimerase [Cell wall/membrane/envelope biogenesis]
    pfam11803
    Location:583
    UXS1_N; UDP-glucuronate decarboxylase N-terminal
  2. NM_001244774.1NP_001231703.1  UDP-glucuronic acid decarboxylase 1 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site in the internal coding region, compared to variant 1. It encodes isoform b, which is shorter than isoform a.
    Source sequence(s)
    AK240525
    UniProtKB/TrEMBL
    A0A8D1N0E3, F1SU22
    Related
    ENSSSCP00000008694.4, ENSSSCT00000008920.5
    Conserved Domains (3) summary
    cd05230
    Location:89392
    UGD_SDR_e; UDP-glucuronate decarboxylase (UGD) and related proteins, extended (e) SDRs
    COG0451
    Location:89396
    WcaG; Nucleoside-diphosphate-sugar epimerase [Cell wall/membrane/envelope biogenesis]
    pfam11803
    Location:578
    UXS1_N; UDP-glucuronate decarboxylase N-terminal

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010445.4 Reference Sscrofa11.1 Primary Assembly

    Range
    48871036..48940736
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021085665.1XP_020941324.1  UDP-glucuronic acid decarboxylase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8D0K1K6, A0A8D1D3S5, A0A8D1UBU5
    Conserved Domains (2) summary
    cd05230
    Location:50353
    UGD_SDR_e; UDP-glucuronate decarboxylase (UGD) and related proteins, extended (e) SDRs
    pfam11803
    Location:139
    UXS1_N; UDP-glucuronate decarboxylase N-terminal
  2. XM_021085666.1XP_020941325.1  UDP-glucuronic acid decarboxylase 1 isoform X2

    Conserved Domains (1) summary
    cd05230
    Location:1284
    UGD_SDR_e; UDP-glucuronate decarboxylase (UGD) and related proteins, extended (e) SDRs
  3. XM_021085667.1XP_020941326.1  UDP-glucuronic acid decarboxylase 1 isoform X2

    Conserved Domains (1) summary
    cd05230
    Location:1284
    UGD_SDR_e; UDP-glucuronate decarboxylase (UGD) and related proteins, extended (e) SDRs