LSM14A LSM14A mRNA processing body assembly factor [Sus scrofa (pig)] - Gene

Summary

Official Symbol: LSM14Aprovided by VGNC
Official Full Name: LSM14A mRNA processing body assembly factorprovided by VGNC
Primary source: VGNC:VGNC:89872
See related: Ensembl:ENSSSCG00000002869
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Sus scrofa
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression: Ubiquitous expression in lung (RPKM 65.1), spleen (RPKM 61.8) and 8 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 6

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
106	current	Sscrofa11.1 (GCF_000003025.6)	6	NC_010448.4 (43847882..43901697)
105	previous assembly	Sscrofa10.2 (GCF_000003025.5)	6	NC_010448.3 (39316239..39340790, complement)

Chromosome 6 - NC_010448.4 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
BioProject: PRJNA311523
Publication: PMID 27646534
Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The expression pattern of LSM14A during the infection of PRRS virus in Tongcheng and Large White pigs was suppressed by the PRRS virus challenge.
Title: LSM14A inhibits porcine reproductive and respiratory syndrome virus (PRRSV) replication by activating IFN-β signaling pathway in Marc-145.
Expression of LSm14A in HEK293 or Marc-145 cells enhanced activities of IFN-beta and NF-kappaB promoters, induced IFN-beta transcription, and potentiated IFN-beta promoter activation, indicating that LSm14A is a potential signal molecule in the IFN-beta pathway.
Title: Functional characterization of porcine LSm14A in IFN-β induction.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables mRNA binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in P-body assembly	IEA Inferred from Electronic Annotation more info	PubMed
involved_in stress granule assembly	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in P-body	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: protein LSM14 homolog A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001315798.1 → NP_001302727.1 protein LSM14 homolog A

Status: PROVISIONAL

Source sequence(s)

KC769582

UniProtKB/TrEMBL

A0A8D0P6Z5, A0A8D0VWA3, R4JU57

Related

ENSSSCP00000055827.1, ENSSSCT00000055533.3

Conserved Domains (2) summary

cd01736
Location:4 → 77

LSm14_N; Like-Sm protein 14, N-terminal domain

pfam09532
Location:291 → 399

FDF; FDF domain