PRPS2 phosphoribosyl pyrophosphate synthetase 2 [Sus scrofa (pig)] - Gene

Summary

Gene symbol: PRPS2
Gene description: phosphoribosyl pyrophosphate synthetase 2
See related: Ensembl:ENSSSCG00000057105
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Sus scrofa
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression: Broad expression in spleen (RPKM 131.9), lung (RPKM 55.7) and 8 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: chromosome: X

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
106	current	Sscrofa11.1 (GCF_000003025.6)	X	NC_010461.5 (9505034..9531044)
105	previous assembly	Sscrofa10.2 (GCF_000003025.5)	X	NC_010461.4 (10404804..10432367)

Chromosome X - NC_010461.5 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Transcriptome data used for gene annotation
Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
BioProject: PRJNA311523
Publication: PMID 27646534
Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables magnesium ion binding	IEA Inferred from Electronic Annotation more info	PubMed
enables ribose phosphate diphosphokinase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in 5-phosphoribose 1-diphosphate biosynthetic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in purine nucleotide biosynthetic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in ribonucleoside monophosphate biosynthetic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
part_of ribose phosphate diphosphokinase complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: ribose-phosphate pyrophosphokinase 2

NP_001230730.1

EC 2.7.6.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001243801.1 → NP_001230730.1 ribose-phosphate pyrophosphokinase 2

Status: VALIDATED

Source sequence(s)

AK239604

UniProtKB/TrEMBL

A0A1B2TT56

Related

ENSSSCP00000063578.2, ENSSSCT00000075462.2

Conserved Domains (3) summary

COG0462
Location:1 → 313

PrsA; Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism, Amino acid transport and metabolism]

pfam13793
Location:4 → 120

Pribosyltran_N; N-terminal domain of ribose phosphate pyrophosphokinase

cl00309
Location:161 → 313

PRTases_typeI; Phosphoribosyl transferase (PRT)-type I domain