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TMEM35B transmembrane protein 35B [ Homo sapiens (human) ]

Gene ID: 100506144, updated on 8-Mar-2024

Summary

Official Symbol
TMEM35Bprovided by HGNC
Official Full Name
transmembrane protein 35Bprovided by HGNC
Primary source
HGNC:HGNC:40021
See related
Ensembl:ENSG00000243749 AllianceGenome:HGNC:40021
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ZMYM6NB
Summary
Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in placenta (RPKM 28.9), thyroid (RPKM 23.1) and 25 other tissues See more
Orthologs
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Genomic context

Location:
1p34.3
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (34981380..34985347, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (34844050..34848018, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (35446981..35450948, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 629 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 718 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 719 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 720 Neighboring gene DLG associated protein 3 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:35350327-35351322 Neighboring gene MPRA-validated peak171 silencer Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 631 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 632 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 634 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 633 Neighboring gene G protein-coupled receptor 199, pseudogene Neighboring gene ReSE screen-validated silencer GRCh37_chr1:35462847-35463058 Neighboring gene zinc finger MYM-type containing 6 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:35496848-35497374 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:35497375-35497899 Neighboring gene uncharacterized LOC124903990

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
transmembrane protein 35B
Names
ZMYM6 neighbor protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001195156.2NP_001182085.1  transmembrane protein 35B precursor

    See identical proteins and their annotated locations for NP_001182085.1

    Status: VALIDATED

    Source sequence(s)
    AC114490
    Consensus CDS
    CCDS53296.1
    UniProtKB/Swiss-Prot
    Q8NCS4
    Related
    ENSP00000362435.3, ENST00000373337.4

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    34981380..34985347 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    34844050..34848018 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)