Nat8f6 N-acetyltransferase 8 (GCN5-related) family member 6 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Nat8f6provided by MGI
Official Full Name: N-acetyltransferase 8 (GCN5-related) family member 6provided by MGI
Primary source: MGI:MGI:3779382
See related: Ensembl:ENSMUSG00000079495 AllianceGenome:MGI:3779382
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Cml3; Nat8f3; Gm11128
Summary: Predicted to enable cysteine-S-conjugate N-acetyltransferase activity and lysine N-acetyltransferase activity, acting on acetyl phosphate as donor. Predicted to be involved in several processes, including negative regulation of apoptotic process; peptide metabolic process; and peptidyl-lysine N6-acetylation. Predicted to be located in endoplasmic reticulum membrane and endoplasmic reticulum-Golgi intermediate compartment membrane. Predicted to be integral component of membrane. Orthologous to human NAT8 (N-acetyltransferase 8 (putative)). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in kidney adult (RPKM 144.2) and lung adult (RPKM 3.8) See more
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Genomic context

Location:: 6 C3; 6 37.48 cM

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	6	NC_000072.7 (85785026..85786859, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	6	NC_000072.6 (85808044..85809877, complement)

Chromosome 6 - NC_000072.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables cysteine-S-conjugate N-acetyltransferase activity	ISO Inferred from Sequence Orthology more info
enables lysine N-acetyltransferase activity, acting on acetyl phosphate as donor	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in endoplasmic reticulum membrane	ISO Inferred from Sequence Orthology more info
located_in endoplasmic reticulum-Golgi intermediate compartment	ISO Inferred from Sequence Orthology more info
located_in endoplasmic reticulum-Golgi intermediate compartment membrane	ISO Inferred from Sequence Orthology more info
located_in membrane	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: camello-like 3-like

Names: Camello-like protein 3; N-acetyltransferase CML3; N-acetyltransferase family 8 member 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001201389.1 → NP_001188318.1 camello-like 3-like

See identical proteins and their annotated locations for NP_001188318.1

Status: VALIDATED

Source sequence(s)

AC162313, AI132313

Consensus CDS

CCDS51830.1

UniProtKB/Swiss-Prot

Q8BQW2, Q91WM7, Q9JIY8

Related

ENSMUSP00000084938.5, ENSMUST00000087656.5

Conserved Domains (2) summary

COG0456
Location:99 → 198

RimI; Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis]

pfam00583
Location:116 → 194

Acetyltransf_1; Acetyltransferase (GNAT) family