U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Ube2q2l ubiquitin conjugating enzyme E2 Q2 like [ Mus musculus (house mouse) ]

Gene ID: 100502936, updated on 17-Aug-2024

Summary

Go to the top of the page Help
Official Symbol
Ube2q2lprovided by MGI
Official Full Name
ubiquitin conjugating enzyme E2 Q2 likeprovided by MGI
Primary source
MGI:MGI:2141773
See related
Ensembl:ENSMUSG00000045291 AllianceGenome:MGI:2141773
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
E330021D16Rik
Summary
Predicted to enable ubiquitin conjugating enzyme activity. Predicted to be involved in protein K48-linked ubiquitination. Predicted to be active in nucleus. Orthologous to human UBE2Q2 (ubiquitin conjugating enzyme E2 Q2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in ovary adult (RPKM 3.0), placenta adult (RPKM 0.8) and 2 other tissues See more
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Ube2q2l in Genome Data Viewer
Location:
6 G1; 6 66.59 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (136377310..136396870, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (136400312..136419873, complement)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 707 pseudogene Neighboring gene tubulin, beta 3 class III, pseudogene 1 Neighboring gene STARR-seq mESC enhancer starr_17592 Neighboring gene predicted gene, 36844 Neighboring gene predicted gene, 53345

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Piao Y, et al. Genome Res, 2001 Sep. PMID 11544199, Free PMC Article
  2. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
  3. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
  4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ubiquitin conjugating enzyme activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ubiquitin-protein transferase activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in protein K48-linked ubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein K48-linked ubiquitination ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
ubiquitin-conjugating enzyme E2 Q2-like
Names
ubiquitin-conjugating enzyme E2Q (putative) 2 pseudogene

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001201390.1 → NP_001188319.1  ubiquitin-conjugating enzyme E2 Q2-like

    See identical proteins and their annotated locations for NP_001188319.1

    Status: VALIDATED

    Source sequence(s)
    AK054382, BM228571
    Consensus CDS
    CCDS51940.1
    UniProtKB/TrEMBL
    Q3TS71, Q8BW45
    Related
    ENSMUSP00000145343.2, ENSMUST00000204830.2
    Conserved Domains (2) summary
    cl00154
    Location:203 → 328
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    cl02687
    Location:8 → 88
    RWD; RWD domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    136377310..136396870 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006505223.5 → XP_006505286.1  ubiquitin-conjugating enzyme E2 Q2-like isoform X1

    See identical proteins and their annotated locations for XP_006505286.1

    UniProtKB/TrEMBL
    Q3TS71, Q8BW45
    Conserved Domains (2) summary
    cl00154
    Location:203 → 328
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    cl02687
    Location:8 → 88
    RWD; RWD domain

  2. XM_011241098.3 → XP_011239400.1  ubiquitin-conjugating enzyme E2 Q2-like isoform X1

    See identical proteins and their annotated locations for XP_011239400.1

    UniProtKB/TrEMBL
    Q3TS71, Q8BW45
    Conserved Domains (2) summary
    cl00154
    Location:203 → 328
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    cl02687
    Location:8 → 88
    RWD; RWD domain

  3. XM_011241097.3 → XP_011239399.1  ubiquitin-conjugating enzyme E2 Q2-like isoform X1

    See identical proteins and their annotated locations for XP_011239399.1

    UniProtKB/TrEMBL
    Q3TS71, Q8BW45
    Conserved Domains (2) summary
    cl00154
    Location:203 → 328
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    cl02687
    Location:8 → 88
    RWD; RWD domain

  4. XM_011241096.1 → XP_011239398.1  ubiquitin-conjugating enzyme E2 Q2-like isoform X1

    See identical proteins and their annotated locations for XP_011239398.1

    UniProtKB/TrEMBL
    Q3TS71, Q8BW45
    Conserved Domains (2) summary
    cl00154
    Location:203 → 328
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    cl02687
    Location:8 → 88
    RWD; RWD domain
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools