asb3 ankyrin repeat and SOCS box containing 3 [Xenopus tropicalis (tropical clawed frog)] - Gene

Summary

Official Symbol: asb3provided by Xenbase
Official Full Name: ankyrin repeat and SOCS box containing 3provided by Xenbase
Primary source: Xenbase:XB-GENE-989169
See related: Ensembl:ENSXETG00000015199 AllianceGenome:Xenbase:XB-GENE-989169
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus tropicalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as: asb-3
Summary: Predicted to act upstream of or within intracellular signal transduction and protein ubiquitination. Orthologous to human GPR75-ASB3 (GPR75-ASB3 readthrough). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 5

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
104	current	UCB_Xtro_10.0 (GCF_000004195.4)	5	NC_030681.2 (23524574..23588767, complement)
103	previous assembly	Xenopus_tropicalis_v9.1 (GCF_000004195.3)	5	NC_030681.1 (19441117..19502170, complement)

Chromosome 5 - NC_030681.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Process	Evidence Code	Pubs
acts_upstream_of_or_within intracellular signal transduction	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein ubiquitination	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: ankyrin repeat and SOCS box protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001205069.1 → NP_001191998.1 ankyrin repeat and SOCS box protein 3

See identical proteins and their annotated locations for NP_001191998.1

Status: PROVISIONAL

Source sequence(s)

AAMC04000005

UniProtKB/TrEMBL

A0A803JJ25, F7A068

Related

ENSXETP00000107931.1, ENSXETT00000110340.1

Conserved Domains (4) summary

PHA02874
Location:17 → 267

PHA02874; ankyrin repeat protein; Provisional

cd03722
Location:456 → 506

SOCS_ASB3; SOCS (suppressors of cytokine signaling) box of ASB3-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ABS3 has been shown to be negative regulator of TNF-R2-mediated cellular responses to TNF-alpha ...

sd00045
Location:78 → 109

ANK; ANK repeat [structural motif]

pfam12796
Location:83 → 176

Ank_2; Ankyrin repeats (3 copies)

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

NC_030681.2 Reference UCB_Xtro_10.0 Primary Assembly

Range

23524574..23588767 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_018093817.2 → XP_017949306.1 ankyrin repeat and SOCS box protein 3 isoform X2

UniProtKB/TrEMBL

A0A8J0T2T1

Conserved Domains (4) summary

PHA02874
Location:17 → 267

PHA02874; ankyrin repeat protein; Provisional

cd03722
Location:372 → 422

SOCS_ASB3; SOCS (suppressors of cytokine signaling) box of ASB3-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ABS3 has been shown to be negative regulator of TNF-R2-mediated cellular responses to TNF-alpha ...

sd00045
Location:78 → 109

ANK; ANK repeat [structural motif]

pfam12796
Location:83 → 176

Ank_2; Ankyrin repeats (3 copies)
XM_012962820.3 → XP_012818274.1 ankyrin repeat and SOCS box protein 3 isoform X1

See identical proteins and their annotated locations for XP_012818274.1

UniProtKB/TrEMBL

A0A803JJ25, F7A068

Related

ENSXETP00000033259.3, ENSXETT00000033259.5

Conserved Domains (4) summary

PHA02874
Location:17 → 267

PHA02874; ankyrin repeat protein; Provisional

cd03722
Location:456 → 506

SOCS_ASB3; SOCS (suppressors of cytokine signaling) box of ASB3-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ABS3 has been shown to be negative regulator of TNF-R2-mediated cellular responses to TNF-alpha ...

sd00045
Location:78 → 109

ANK; ANK repeat [structural motif]

pfam12796
Location:83 → 176

Ank_2; Ankyrin repeats (3 copies)
XM_012962821.3 → XP_012818275.1 ankyrin repeat and SOCS box protein 3 isoform X1

See identical proteins and their annotated locations for XP_012818275.1

UniProtKB/TrEMBL

A0A803JJ25, F7A068

Conserved Domains (4) summary

PHA02874
Location:17 → 267

PHA02874; ankyrin repeat protein; Provisional

cd03722
Location:456 → 506

SOCS_ASB3; SOCS (suppressors of cytokine signaling) box of ASB3-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ABS3 has been shown to be negative regulator of TNF-R2-mediated cellular responses to TNF-alpha ...

sd00045
Location:78 → 109

ANK; ANK repeat [structural motif]

pfam12796
Location:83 → 176

Ank_2; Ankyrin repeats (3 copies)