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mettl23 methyltransferase 23, arginine [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 100496624, updated on 14-Nov-2024

Summary

Official Symbol
mettl23provided by Xenbase
Official Full Name
methyltransferase 23, arginineprovided by Xenbase
Primary source
Xenbase:XB-GENE-6034943
See related
Ensembl:ENSXETG00000019499 AllianceGenome:Xenbase:XB-GENE-6034943
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
c17orf95
Summary
Predicted to enable methyltransferase activity. Predicted to act upstream of or within methylation. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 44. Orthologous to human METTL23 (methyltransferase 23, arginine). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See mettl23 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
5
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 10 NC_030686.2 (45534339..45537687)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 10 NC_030686.1 (36949704..36953001)

Chromosome 10 - NC_030686.2Genomic Context describing neighboring genes Neighboring gene matrix-remodelling associated 7 Neighboring gene jumonji domain containing 6 Neighboring gene serine/arginine-rich splicing factor 2 Neighboring gene major facilitator superfamily domain containing 11

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables histone H3R17 methyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in epigenetic regulation of gene expression IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within methylation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
methyltransferase-like protein 23
Names
UPF0563 protein C17orf95 homolog
methyltransferase like 23

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030686.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    45534339..45537687
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002935924.5XP_002935970.2  methyltransferase-like protein 23

    UniProtKB/TrEMBL
    F6RLY3
    Related
    ENSXETP00000042225.3, ENSXETT00000042225.4
    Conserved Domains (1) summary
    cl17173
    Location:40164
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...