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st6gal1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 100491268, updated on 4-Nov-2024

Summary

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Official Symbol
st6gal1provided by Xenbase
Official Full Name
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1provided by Xenbase
Primary source
Xenbase:XB-GENE-983202
See related
Ensembl:ENSXETG00000041175 AllianceGenome:Xenbase:XB-GENE-983202
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Summary
Predicted to enable sialyltransferase activity. Predicted to act upstream of or within protein glycosylation. Predicted to be located in Golgi cisterna membrane. Orthologous to human ST6GAL1 (ST6 beta-galactoside alpha-2,6-sialyltransferase 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See st6gal1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
9
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 5 NC_030681.2 (127493835..127531283)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 5 NC_030681.1 (123915504..123957941)

Chromosome 5 - NC_030681.2Genomic Context describing neighboring genes Neighboring gene COP9 signalosome subunit 9 Neighboring gene adiponectin, C1Q and collagen domain containing Neighboring gene transfer RNA glycine (anticodon CCC) Neighboring gene transfer RNA glycine (anticodon CCC)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
  
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables sialyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within protein glycosylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
located_in Golgi cisterna membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
beta-galactoside alpha-2,6-sialyltransferase 1
NP_001243216.1
XP_012825671.2
XP_012825672.2
XP_012825674.2
XP_012825675.2
XP_031757448.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001256287.1 → NP_001243216.1  beta-galactoside alpha-2,6-sialyltransferase 1

    See identical proteins and their annotated locations for NP_001243216.1

    Status: PROVISIONAL

    Source sequence(s)
    FN996984
    UniProtKB/TrEMBL
    E4ZFH6
    Conserved Domains (3) summary
    pfam00777
    Location:245 → 449
    Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)
    cd16269
    Location:128 → 139
    GBP_C; coiled coil [structural motif]
    cl20817
    Location:63 → 141
    GBP_C; Guanylate-binding protein, C-terminal domain

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030681.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    127493835..127531283
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012970217.3 → XP_012825671.2  beta-galactoside alpha-2,6-sialyltransferase 1 isoform X1

    UniProtKB/TrEMBL
    A0A6I8RQD2
    Conserved Domains (2) summary
    pfam17380
    Location:57 → 153
    DUF5401; Family of unknown function (DUF5401)
    pfam00777
    Location:233 → 449
    Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

  2. XM_012970220.3 → XP_012825674.2  beta-galactoside alpha-2,6-sialyltransferase 1 isoform X1

    UniProtKB/TrEMBL
    A0A6I8RQD2
    Conserved Domains (2) summary
    pfam17380
    Location:57 → 153
    DUF5401; Family of unknown function (DUF5401)
    pfam00777
    Location:233 → 449
    Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

  3. XM_012970218.3 → XP_012825672.2  beta-galactoside alpha-2,6-sialyltransferase 1 isoform X1

    UniProtKB/TrEMBL
    A0A6I8RQD2
    Conserved Domains (2) summary
    pfam17380
    Location:57 → 153
    DUF5401; Family of unknown function (DUF5401)
    pfam00777
    Location:233 → 449
    Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

  4. XM_012970221.3 → XP_012825675.2  beta-galactoside alpha-2,6-sialyltransferase 1 isoform X1

    UniProtKB/TrEMBL
    A0A6I8RQD2
    Conserved Domains (2) summary
    pfam17380
    Location:57 → 153
    DUF5401; Family of unknown function (DUF5401)
    pfam00777
    Location:233 → 449
    Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

  5. XM_031901588.1 → XP_031757448.1  beta-galactoside alpha-2,6-sialyltransferase 1 isoform X1

    UniProtKB/TrEMBL
    A0A6I8RQD2
    Related
    ENSXETP00000084826.2, ENSXETT00000090509.2
    Conserved Domains (2) summary
    pfam17380
    Location:57 → 153
    DUF5401; Family of unknown function (DUF5401)
    pfam00777
    Location:233 → 449
    Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)
Nucleotide Protein Strain
Heading Accession and Version

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