mtr 5-methyltetrahydrofolate-homocysteine methyltransferase [Xenopus tropicalis (tropical clawed frog)] - Gene

Summary

Official Symbol: mtrprovided by Xenbase
Official Full Name: 5-methyltetrahydrofolate-homocysteine methyltransferaseprovided by Xenbase
Primary source: Xenbase:XB-GENE-1001004
See related: Ensembl:ENSXETG00000018453 AllianceGenome:Xenbase:XB-GENE-1001004
Gene type: protein coding
RefSeq status: MODEL
Organism: Xenopus tropicalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Summary: Predicted to enable cobalamin binding activity; methionine synthase activity; and zinc ion binding activity. Predicted to act upstream of or within methionine biosynthetic process; methylation; and pteridine-containing compound metabolic process. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in several diseases, including IgA glomerulonephritis; artery disease (multiple); autistic disorder; hematologic cancer (multiple); and hyperhomocysteinemia. Orthologous to human MTR (5-methyltetrahydrofolate-homocysteine methyltransferase). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Annotation release	Status	Assembly	Chr	Location
104	current	UCB_Xtro_10.0 (GCF_000004195.4)	5	NC_030681.2 (41959550..42000466)
103	previous assembly	Xenopus_tropicalis_v9.1 (GCF_000004195.3)	5	NC_030681.1 (52128163..52169085)

Chromosome 5 - NC_030681.2 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables cobalamin binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables methionine synthase activity	IEA Inferred from Electronic Annotation more info
enables methyltransferase activity	IEA Inferred from Electronic Annotation more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within methionine biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within methylation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within pteridine-containing compound metabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within sulfur compound metabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info

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The following sections contain reference sequences that belong to a specific genome build. Explain