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wfikkn2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 100486381, updated on 4-Nov-2024

Summary

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Official Symbol
wfikkn2provided by Xenbase
Official Full Name
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2provided by Xenbase
Primary source
Xenbase:XB-GENE-922961
See related
Ensembl:ENSXETG00000025275 AllianceGenome:Xenbase:XB-GENE-922961
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Summary
Orthologous to human WFIKKN2 (WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See wfikkn2 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
2
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 10 NC_030686.2 (46114324..46119147, complement)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 10 NC_030686.1 (37535101..37539655, complement)

Chromosome 10 - NC_030686.2Genomic Context describing neighboring genes Neighboring gene brain specific kinase 146 Neighboring gene ATP binding cassette subfamily C member 3 Neighboring gene nuclear prelamin A recognition factor Neighboring gene cytochrome b-245 chaperone 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

General protein information

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Preferred Names
WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030686.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    46114324..46119147 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018097885.2 → XP_017953374.2  WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2

    Related
    ENSXETP00000054046.4, ENSXETT00000054046.4
    Conserved Domains (6) summary
    smart00131
    Location:310 → 362
    KU; BPTI/Kunitz family of serine protease inhibitors
    cd00104
    Location:126 → 162
    KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...
    cd03575
    Location:438 → 546
    NTR_WFIKKN; NTR domain, WFIKKN subfamily; WFIKKN proteins contain a C-terminal NTR domain and are putative secreted proteins which may be multivalent protease inhibitors that act on serine proteases as well as metalloproteases. Human WFIKKN and a related protein ...
    pfam00014
    Location:369 → 420
    Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
    pfam00095
    Location:30 → 79
    WAP; WAP-type (Whey Acidic Protein) 'four-disulfide core'
    cd05765
    Location:198 → 292
    IgI_3_WFIKKN-like; Third immunoglobulin-like domain of the human WFIKKN (WAP, follistatin, immunoglobulin, Kunitz and NTR domain-containing protein), and similar domains; member of the I-set of Ig superfamily (IgSF) domains
Nucleotide Protein Strain
Heading Accession and Version

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