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arhgef3.2 Rho guanine nucleotide exchange factor 3 [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 100486292, updated on 4-Nov-2024

Summary

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Official Symbol
arhgef3.2provided by Xenbase
Official Full Name
Rho guanine nucleotide exchange factor 3provided by Xenbase
Primary source
Xenbase:XB-GENE-993949
See related
Ensembl:ENSXETG00000000921 AllianceGenome:Xenbase:XB-GENE-993949
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
gef3; sta3; xpln; arhgef3
Summary
Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to act upstream of or within intracellular signal transduction. Predicted to be located in cytoplasm. Orthologous to human ARHGEF3 (Rho guanine nucleotide exchange factor 3). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See arhgef3.2 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
14
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 4 NC_030680.2 (148811059..148954964)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) Unplaced Scaffold NW_016683391.1 (21098..106777)

Chromosome 4 - NC_030680.2Genomic Context describing neighboring genes Neighboring gene HESX homeobox 1 Neighboring gene interleukin 17 receptor D Neighboring gene transcription activation suppressor Neighboring gene coiled-coil domain containing 66

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
rho guanine nucleotide exchange factor 3
Names
Rho guanine nucleotide exchange factor (GEF) 3, gene 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030680.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    148811059..148954964
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031901259.1 → XP_031757119.1  rho guanine nucleotide exchange factor 3 isoform X1

    UniProtKB/TrEMBL
    A0A1B8Y8X4, A0A6I8SM13, F6X933
    Related
    ENSXETP00000093167.2, ENSXETT00000068493.2
    Conserved Domains (2) summary
    smart00325
    Location:159 → 335
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cd10572
    Location:349 → 481
    PH_RhoGEF3_XPLN; Rho guanine nucleotide exchange factor 3 Pleckstrin homology (PH) domain

  2. XM_004914175.4 → XP_004914232.1  rho guanine nucleotide exchange factor 3 isoform X2

    UniProtKB/TrEMBL
    A0A1B8Y8X4, A0A6I8SV86, F6X933
    Related
    ENSXETP00000096247.1, ENSXETT00000095679.2
    Conserved Domains (2) summary
    smart00325
    Location:127 → 303
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cd10572
    Location:317 → 449
    PH_RhoGEF3_XPLN; Rho guanine nucleotide exchange factor 3 Pleckstrin homology (PH) domain

  3. XM_002940029.5 → XP_002940075.2  rho guanine nucleotide exchange factor 3 isoform X3

    UniProtKB/TrEMBL
    A0A1B8Y8X4, A0A7D9NKU0, F6X933
    Related
    ENSXETP00000090358.1, ENSXETT00000091531.2
    Conserved Domains (2) summary
    smart00325
    Location:126 → 302
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cd10572
    Location:316 → 448
    PH_RhoGEF3_XPLN; Rho guanine nucleotide exchange factor 3 Pleckstrin homology (PH) domain
Nucleotide Protein Strain
Heading Accession and Version

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