U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

rc3h1 ring finger and CCCH-type domains 1 [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 100485305, updated on 4-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
rc3h1provided by Xenbase
Official Full Name
ring finger and CCCH-type domains 1provided by Xenbase
Primary source
Xenbase:XB-GENE-5864196
See related
Ensembl:ENSXETG00000020030 AllianceGenome:Xenbase:XB-GENE-5864196
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Summary
Predicted to enable RNA binding activity and ubiquitin protein ligase activity. Predicted to be involved in nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; protein polyubiquitination; and ubiquitin-dependent protein catabolic process. Predicted to be located in P-body. Predicted to be active in cytoplasmic stress granule. Orthologous to human RC3H1 (ring finger and CCCH-type domains 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See rc3h1 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
20
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 4 NC_030680.2 (98005384..98059581)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 4 NC_030680.1 (87813600..87870932)

Chromosome 4 - NC_030680.2Genomic Context describing neighboring genes Neighboring gene aspartyl-tRNA synthetase 2, mitochondrial Neighboring gene RAB GTPase activating protein 1-like Neighboring gene G protein-coupled receptor 52 Neighboring gene serpin peptidase inhibitor, clade C (antithrombin), member 1 Neighboring gene zinc finger and BTB domain containing 37

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables RNA stem-loop binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables double-stranded RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
enables ubiquitin protein ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein polyubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in P-body IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytoplasmic stress granule IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
roquin-1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030680.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    98005384..98059581
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004914022.4 → XP_004914079.1  roquin-1 isoform X2

    UniProtKB/TrEMBL
    A0A6I8SI84, A0A8J0QYY6
    Related
    ENSXETP00000098010.2, ENSXETT00000072939.2
    Conserved Domains (2) summary
    smart00184
    Location:14 → 52
    RING; Ring finger
    pfam00642
    Location:416 → 442
    zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)

  2. XM_002931435.5 → XP_002931481.1  roquin-1 isoform X1

    UniProtKB/TrEMBL
    A0A6I8SI84, F7C1X9
    Related
    ENSXETP00000043285.4, ENSXETT00000043285.5
    Conserved Domains (4) summary
    PHA03247
    Location:525 → 785
    PHA03247; large tegument protein UL36; Provisional
    cd16638
    Location:11 → 54
    mRING-HC-C3HC3D_Roquin; Modified RING finger, HC subclass (C3HC3D-type), found in Roquin-1, Roquin-2, and similar proteins
    pfam00642
    Location:416 → 441
    zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
    pfam18386
    Location:273 → 328
    ROQ_II; Roquin II domain

  3. XM_004914024.4 → XP_004914081.1  roquin-1 isoform X4

    UniProtKB/TrEMBL
    A0A6I8SI84, A0A8J0R3S4
    Conserved Domains (3) summary
    cd16638
    Location:11 → 54
    mRING-HC-C3HC3D_Roquin; Modified RING finger, HC subclass (C3HC3D-type), found in Roquin-1, Roquin-2, and similar proteins
    pfam00642
    Location:416 → 441
    zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
    pfam18386
    Location:273 → 328
    ROQ_II; Roquin II domain

  4. XM_004914023.4 → XP_004914080.1  roquin-1 isoform X3

    UniProtKB/TrEMBL
    A0A6I8SI84, A0A803JP22
    Related
    ENSXETP00000109707.1, ENSXETT00000111072.1
    Conserved Domains (4) summary
    PHA03247
    Location:523 → 783
    PHA03247; large tegument protein UL36; Provisional
    cd16638
    Location:11 → 54
    mRING-HC-C3HC3D_Roquin; Modified RING finger, HC subclass (C3HC3D-type), found in Roquin-1, Roquin-2, and similar proteins
    pfam00642
    Location:414 → 439
    zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
    pfam18386
    Location:273 → 325
    ROQ_II; Roquin II domain
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.