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ALOX5 arachidonate 5-lipoxygenase [ Ailuropoda melanoleuca (giant panda) ]

Gene ID: 100476416, updated on 8-Mar-2024

Summary

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Gene symbol
ALOX5
Gene description
arachidonate 5-lipoxygenase
Locus tag
PANDA_015920
See related
Ensembl:ENSAMEG00000007692
Gene type
protein coding
RefSeq status
MODEL
Organism
Ailuropoda melanoleuca
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ailuropoda
Orthologs
human mouse all
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Genomic context

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See ALOX5 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
15
Annotation release Status Assembly Chr Location
103 current ASM200744v2 (GCF_002007445.1) 6 NC_048223.1 (90762144..90822990, complement)
102 previous assembly AilMel_1.0 (GCF_000004335.2) Unplaced Scaffold NW_003218349.1 (638640..689881, complement)

Chromosome 6 - NC_048223.1Genomic Context describing neighboring genes Neighboring gene plasminogen activator inhibitor 1 RNA-binding protein-like Neighboring gene membrane associated ring-CH-type finger 8 Neighboring gene uncharacterized LOC117802715 Neighboring gene olfactory receptor 13A1 Neighboring gene olfactory receptor 2AP1-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The sequence and de novo assembly of the giant panda genome. Li R, et al. Nature, 2010 Jan 21. PMID 20010809, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables arachidonate 5-lipoxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in linoleic acid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipid oxidation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nuclear envelope IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
arachidonate 5-lipoxygenase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Ailuropoda melanoleuca Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM200744v2 Primary Assembly

Genomic

  1. NC_048223.1 Reference ASM200744v2 Primary Assembly

    Range
    90762144..90822990 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002926245.4 → XP_002926291.1  arachidonate 5-lipoxygenase isoform X2

    See identical proteins and their annotated locations for XP_002926291.1

    UniProtKB/TrEMBL
    A0A7N5P2J6, D2HUH1, G1LMI8
    Related
    ENSAMEP00000008227.2, ENSAMET00000008569.2
    Conserved Domains (2) summary
    cd01753
    Location:2 → 115
    PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...
    pfam00305
    Location:227 → 665
    Lipoxygenase; Lipoxygenase

  2. XM_034662871.1 → XP_034518762.1  arachidonate 5-lipoxygenase isoform X1

Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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