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THBS1 thrombospondin 1 [ Pongo abelii (Sumatran orangutan) ]

Gene ID: 100453386, updated on 26-Mar-2024

Summary

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Gene symbol
THBS1
Gene description
thrombospondin 1
Locus tag
CR201_G0038117
See related
Ensembl:ENSPPYG00000006338
Gene type
protein coding
RefSeq status
MODEL
Organism
Pongo abelii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
Orthologs
human mouse all
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Genomic context

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See THBS1 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2) 16 NC_072001.2 (42473689..42490035)
RS_2023_04 previous assembly NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1) 15 NC_072000.1 (39753372..39769689)

Chromosome 16 - NC_072001.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC129050081 Neighboring gene uncharacterized LOC129050084 Neighboring gene fibrous sheath interacting protein 1 Neighboring gene G protein-coupled receptor 176 Neighboring gene uncharacterized LOC100939277

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of angiogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in collagen-containing extracellular matrix IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
thrombospondin-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028885655.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

Genomic

  1. NC_072001.2 Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

    Range
    42473689..42490035
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063716574.1 → XP_063572644.1  thrombospondin-1 isoform X1

  2. XM_002825281.6 → XP_002825327.1  thrombospondin-1 isoform X2

    UniProtKB/TrEMBL
    A0A2J8T2X7, A0A663D9A9, H2NMT2
    Related
    ENSPPYP00000007178.2
    Conserved Domains (10) summary
    smart00209
    Location:438 → 490
    TSP1; Thrombospondin type 1 repeats
    smart00210
    Location:26 → 221
    TSPN; Thrombospondin N-terminal -like domains
    sd00001
    Location:845 → 882
    TSP3; TSP3 repeat_long [structural motif]
    sd00002
    Location:787 → 821
    TSP3; TSP3 repeat_long [structural motif]
    sd00003
    Location:691 → 726
    TSP3_1C; TSP3 repeat_1C [structural motif]
    pfam00093
    Location:318 → 372
    VWC; von Willebrand factor type C domain
    pfam00090
    Location:383 → 428
    TSP_1; Thrombospondin type 1 domain
    pfam02412
    Location:846 → 882
    TSP_3; Thrombospondin type 3 repeat
    pfam05735
    Location:972 → 1169
    TSP_C; Thrombospondin C-terminal region
    pfam12947
    Location:650 → 689
    EGF_3; EGF domain
Nucleotide Protein
Heading Accession and Version

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