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ALG2 ALG2 alpha-1,3/1,6-mannosyltransferase [ Pongo abelii (Sumatran orangutan) ]

Gene ID: 100451740, updated on 18-Sep-2024

Summary

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Gene symbol
ALG2
Gene description
ALG2 alpha-1,3/1,6-mannosyltransferase
Locus tag
CR201_G0008216
See related
Ensembl:ENSPPYG00000019440
Gene type
protein coding
RefSeq status
MODEL
Organism
Pongo abelii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
Orthologs
human mouse all
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Genomic context

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See ALG2 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2) 13 NC_071998.2 (90259717..90264307, complement)
RS_2023_04 previous assembly NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1) 9 NC_071994.1 (74611209..74615759, complement)

Chromosome 13 - NC_071998.2Genomic Context describing neighboring genes Neighboring gene collagen type XV alpha 1 chain Neighboring gene transforming growth factor beta receptor 1 Neighboring gene SEC61 translocon subunit beta Neighboring gene keratin, type II cytoskeletal 8-like Neighboring gene uncharacterized LOC129047951

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables alpha-1,3-mannosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein glycosylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endomembrane system IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
alpha-1,3/1,6-mannosyltransferase ALG2
Names
asparagine-linked glycosylation 2, alpha-1,3-mannosyltransferase homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028885655.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

Genomic

  1. NC_071998.2 Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

    Range
    90259717..90264307 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002820031.5 → XP_002820077.1  alpha-1,3/1,6-mannosyltransferase ALG2

    UniProtKB/TrEMBL
    A0A2J8WSI5, A0A663DGW5, H2PSW0
    Related
    ENSPPYP00000021784.1
    Conserved Domains (1) summary
    cd03805
    Location:16 → 407
    GT1_ALG2_like; This family is most closely related to the GT1 family of glycosyltransferases. ALG2, a 1,3-mannosyltransferase, in yeast catalyzes the mannosylation of Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2) ...
Nucleotide Protein
Heading Accession and Version

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Molecular Biology Databases
Research Materials