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LIN7A lin-7 homolog A, crumbs cell polarity complex component [ Pongo abelii (Sumatran orangutan) ]

Gene ID: 100448475, updated on 26-Mar-2024

Summary

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Gene symbol
LIN7A
Gene description
lin-7 homolog A, crumbs cell polarity complex component
Locus tag
CR201_G0042789
See related
Ensembl:ENSPPYG00000039262
Gene type
protein coding
RefSeq status
MODEL
Organism
Pongo abelii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
Orthologs
human mouse all
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Genomic context

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See LIN7A in Genome Data Viewer
Location:
chromosome: 10
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2) 10 NC_071995.2 (78969255..79112282, complement)
RS_2023_04 previous assembly NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1) 12 NC_071997.1 (78970111..79113138, complement)

Chromosome 10 - NC_071995.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103892097 Neighboring gene myogenic factor 5 Neighboring gene acyl-CoA synthetase short chain family member 3 Neighboring gene PTPRF interacting protein alpha 2 Neighboring gene collagen alpha-1(I) chain-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables L27 domain binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in maintenance of epithelial cell apical/basal polarity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in neurotransmitter secretion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein localization to basolateral plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of MPP7-DLG1-LIN7 complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in basolateral plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cell-cell junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in synapse IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protein lin-7 homolog A

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028885655.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

Genomic

  1. NC_071995.2 Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

    Range
    78969255..79112282 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002823547.5 → XP_002823593.1  protein lin-7 homolog A

    See identical proteins and their annotated locations for XP_002823593.1

    UniProtKB/TrEMBL
    A0A6D2WJ67, A0A8I5TUF1
    Related
    ENSPPYP00000032550.1
    Conserved Domains (2) summary
    smart00569
    Location:31 → 83
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd00992
    Location:106 → 187
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
Nucleotide Protein
Heading Accession and Version

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