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HAGH hydroxyacylglutathione hydrolase [ Pongo abelii (Sumatran orangutan) ]

Gene ID: 100438197, updated on 10-Oct-2024

Summary

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Gene symbol
HAGH
Gene description
hydroxyacylglutathione hydrolase
Locus tag
CR201_G0052664
See related
Ensembl:ENSPPYG00000006966
Gene type
protein coding
RefSeq status
MODEL
Organism
Pongo abelii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
Orthologs
human mouse all
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Genomic context

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See HAGH in Genome Data Viewer
Location:
chromosome: 18
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2) 18 NC_072003.2 (1913259..1929155, complement)
RS_2023_04 previous assembly NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1) 16 NC_072001.1 (1913550..1929452, complement)

Chromosome 18 - NC_072003.2Genomic Context describing neighboring genes Neighboring gene NUBP iron-sulfur cluster assembly factor 2, cytosolic Neighboring gene insulin like growth factor binding protein acid labile subunit Neighboring gene fumarylacetoacetate hydrolase domain containing 1 Neighboring gene meiosis specific with OB-fold Neighboring gene uncharacterized LOC129050896

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hydroxyacylglutathione hydrolase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in glutathione metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hydroxyacylglutathione hydrolase, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028885655.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

Genomic

  1. NC_072003.2 Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

    Range
    1913259..1929155 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024234103.3 → XP_024089871.1  hydroxyacylglutathione hydrolase, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A2J8R9B7, H2NPR1
    Related
    ENSPPYP00000007887.3
    Conserved Domains (1) summary
    cl25711
    Location:50 → 305
    HAGH_C; Hydroxyacylglutathione hydrolase C-terminus

  2. XM_024234104.3 → XP_024089872.1  hydroxyacylglutathione hydrolase, mitochondrial isoform X3

    UniProtKB/TrEMBL
    A0A2J8R994, A0A2J8R9A6
    Conserved Domains (1) summary
    PLN02469
    Location:1 → 256
    PLN02469; hydroxyacylglutathione hydrolase

  3. XM_024234105.3 → XP_024089873.2  hydroxyacylglutathione hydrolase, mitochondrial isoform X4

  4. XM_063717475.1 → XP_063573545.1  hydroxyacylglutathione hydrolase, mitochondrial isoform X1

Nucleotide Protein
Heading Accession and Version

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