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ZNF722 zinc finger protein 722 [ Homo sapiens (human) ]

Gene ID: 100419780, updated on 8-Mar-2024

Summary

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Official Symbol
ZNF722provided by HGNC
Official Full Name
zinc finger protein 722provided by HGNC
Primary source
HGNC:HGNC:22571
See related
Ensembl:ENSG00000241149 AllianceGenome:HGNC:22571
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ZNF722P
Summary
Predicted to enable metal ion binding activity. Predicted to be involved in regulation of transcription, DNA-templated. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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Location:
7q11.21
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (63998849..64018081)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (65206725..65225970)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (63459227..63478459)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene vomeronasal 1 receptor 36 pseudogene Neighboring gene zinc finger protein 736-like Neighboring gene long intergenic non-protein coding RNA 1005 Neighboring gene uncharacterized LOC105375317

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Gain, loss and divergence in primate zinc-finger genes: a rich resource for evolution of gene regulatory differences between species. Nowick K, et al. PLoS One, 2011. PMID 21738707, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
zinc finger protein 722
Names
zinc finger protein 479 pseudogene
zinc finger protein 722, pseudogene

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001396012.1 → NP_001382941.1  zinc finger protein 722

    Status: VALIDATED

    Source sequence(s)
    AC092634, AC115220
    Consensus CDS
    CCDS94108.1
    UniProtKB/Swiss-Prot
    A0A1W2PQL4
    Related
    ENSP00000492202.1, ENST00000330020.5
    Conserved Domains (3) summary
    smart00349
    Location:16 → 76
    KRAB; krueppel associated box
    COG5048
    Location:211 → 376
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:215 → 235
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

    Range
    63998849..64018081
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060931.1 Alternate T2T-CHM13v2.0

    Range
    65206725..65225970
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NG_026584.2: Suppressed sequence

    Description
    NG_026584.2: This RefSeq was removed because it is now thought that this pseudogene is transcribed.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A1W2PQL4.1 GenPept UniProtKB/Swiss-Prot:A0A1W2PQL4

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials