ATG7 autophagy related 7 [Callithrix jacchus (white-tufted-ear marmoset)] - Gene

Summary

Gene symbol: ATG7
Gene description: autophagy related 7
See related: Ensembl:ENSCJAG00000016583
Gene type: protein coding
RefSeq status: MODEL
Organism: Callithrix jacchus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae; Callitrichinae; Callithrix; Callithrix
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 15

Exon count:: 25

Annotation release	Status	Assembly	Chr	Location
RS_2023_03	current	mCalJa1.2.pat.X (GCF_011100555.1)	15	NC_071456.1 (62445170..62726442)
105	previous assembly	Callithrix_jacchus_cj1700_1.1 (GCF_009663435.1)	15	NC_048397.1 (62996858..63269205)

Chromosome 15 - NC_071456.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables Atg12 activating enzyme activity	IEA Inferred from Electronic Annotation more info	PubMed
enables Atg8 activating enzyme activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in C-terminal protein lipidation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in autophagosome assembly	IEA Inferred from Electronic Annotation more info	PubMed
involved_in autophagy of mitochondrion	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cellular response to nitrogen starvation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in piecemeal microautophagy of the nucleus	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein modification by small protein conjugation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in phagophore assembly site	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: ubiquitin-like modifier-activating enzyme ATG7

Names: ATG7 autophagy related 7 homolog; autophagy related protein 7-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_011100555.1-RS_2023_03

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mCalJa1.2.pat.X

Genomic

NC_071456.1 Reference mCalJa1.2.pat.X

Range

62445170..62726442

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_035273645.2 → XP_035129536.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X3

UniProtKB/TrEMBL

F7H3P8

Conserved Domains (1) summary

TIGR01381
Location:15 → 695

E1_like_apg7; E1-like protein-activating enzyme Gsa7p/Apg7p
XM_035273648.2 → XP_035129539.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X4

UniProtKB/TrEMBL

F7GQW7, F7H3P8

Conserved Domains (1) summary

TIGR01381
Location:15 → 702

E1_like_apg7; E1-like protein-activating enzyme Gsa7p/Apg7p
XM_054245937.1 → XP_054101912.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X3

UniProtKB/TrEMBL

F7H3P8
XM_054245934.1 → XP_054101909.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X1

UniProtKB/TrEMBL

A0A8I3ZZR1
XM_035273643.2 → XP_035129534.2 ubiquitin-like modifier-activating enzyme ATG7 isoform X2

UniProtKB/TrEMBL

A0A8I3ZZR1
XM_035273644.2 → XP_035129535.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X3

UniProtKB/TrEMBL

F7H3P8

Conserved Domains (1) summary

TIGR01381
Location:15 → 695

E1_like_apg7; E1-like protein-activating enzyme Gsa7p/Apg7p
XM_054245936.1 → XP_054101911.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X3

UniProtKB/TrEMBL

F7H3P8
XM_054245935.1 → XP_054101910.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X3

UniProtKB/TrEMBL

F7H3P8
XM_035273646.2 → XP_035129537.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X3

UniProtKB/TrEMBL

F7H3P8

Conserved Domains (1) summary

TIGR01381
Location:15 → 695

E1_like_apg7; E1-like protein-activating enzyme Gsa7p/Apg7p
XM_035273651.2 → XP_035129542.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X5

Conserved Domains (2) summary

cd01486
Location:85 → 410

Apg7; Apg7 is an E1-like protein, that activates two different ubiquitin-like proteins, Apg12 and Apg8, and assigns them to specific E2 enzymes, Apg10 and Apg3, respectively. This leads to the covalent conjugation of Apg8 with phosphatidylethanolamine, an ...

pfam16420
Location:1 → 51

ATG7_N; Ubiquitin-like modifier-activating enzyme ATG7 N-terminus
XM_035273652.2 → XP_035129543.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X6

Conserved Domains (1) summary

cd01486
Location:46 → 371

Apg7; Apg7 is an E1-like protein, that activates two different ubiquitin-like proteins, Apg12 and Apg8, and assigns them to specific E2 enzymes, Apg10 and Apg3, respectively. This leads to the covalent conjugation of Apg8 with phosphatidylethanolamine, an ...