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MASP1 MBL associated serine protease 1 [ Callithrix jacchus (white-tufted-ear marmoset) ]

Gene ID: 100407253, updated on 8-Mar-2024

Summary

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Gene symbol
MASP1
Gene description
MBL associated serine protease 1
See related
Ensembl:ENSCJAG00000014429
Gene type
protein coding
RefSeq status
MODEL
Organism
Callithrix jacchus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae; Callitrichinae; Callithrix; Callithrix
Orthologs
human mouse all
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Genomic context

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See MASP1 in Genome Data Viewer
Location:
chromosome: 15
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2023_03 current mCalJa1.2.pat.X (GCF_011100555.1) 15 NC_071456.1 (9926114..10000879, complement)
105 previous assembly Callithrix_jacchus_cj1700_1.1 (GCF_009663435.1) 15 NC_048397.1 (10645756..10720945, complement)

Chromosome 15 - NC_071456.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein L39 like Neighboring gene receptor transporter protein 1 Neighboring gene receptor transporter protein 4 Neighboring gene small nucleolar RNA U13 Neighboring gene somatostatin

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. De novo assembly of the common marmoset transcriptome from NextGen mRNA sequences. Maudhoo MD, et al. Gigascience, 2014. PMID 25243066, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in complement activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in zymogen activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in blood microparticle IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
mannan-binding lectin serine protease 1
Names
mannan binding lectin serine peptidase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_011100555.1-RS_2023_03

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mCalJa1.2.pat.X

Genomic

  1. NC_071456.1 Reference mCalJa1.2.pat.X

    Range
    9926114..10000879 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008981372.4 → XP_008979620.1  mannan-binding lectin serine protease 1 isoform X4

    Conserved Domains (6) summary
    smart00020
    Location:474 → 717
    Tryp_SPc; Trypsin-like serine protease
    cd00041
    Location:54 → 163
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    cd00190
    Location:475 → 720
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam00084
    Location:327 → 388
    Sushi; Sushi repeat (SCR repeat)
    pfam00431
    Location:211 → 320
    CUB; CUB domain
    pfam14670
    Location:179 → 207
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  2. XM_002758162.7 → XP_002758208.2  mannan-binding lectin serine protease 1 isoform X6

    UniProtKB/TrEMBL
    F6R2R9
    Related
    ENSCJAP00000021257.2
    Conserved Domains (6) summary
    smart00020
    Location:448 → 691
    Tryp_SPc; Trypsin-like serine protease
    cd00041
    Location:28 → 137
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    cd00190
    Location:449 → 694
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam00084
    Location:301 → 362
    Sushi; Sushi repeat (SCR repeat)
    pfam00431
    Location:185 → 294
    CUB; CUB domain
    pfam14670
    Location:153 → 181
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  3. XM_035274725.2 → XP_035130616.2  mannan-binding lectin serine protease 1 isoform X7

  4. XM_008981370.4 → XP_008979618.1  mannan-binding lectin serine protease 1 isoform X1

    UniProtKB/TrEMBL
    F7I992
    Conserved Domains (6) summary
    smart00020
    Location:475 → 737
    Tryp_SPc; Trypsin-like serine protease
    cd00041
    Location:54 → 163
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    cd00190
    Location:476 → 737
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam00084
    Location:327 → 388
    Sushi; Sushi repeat (SCR repeat)
    pfam00431
    Location:211 → 320
    CUB; CUB domain
    pfam14670
    Location:179 → 207
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  5. XM_008981371.5 → XP_008979619.1  mannan-binding lectin serine protease 1 isoform X3

    See identical proteins and their annotated locations for XP_008979619.1

    UniProtKB/TrEMBL
    F7I992, F7I9A8, U3FSL2
    Conserved Domains (5) summary
    smart00020
    Location:449 → 711
    Tryp_SPc; Trypsin-like serine protease
    cd00041
    Location:28 → 137
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam00431
    Location:185 → 294
    CUB; CUB domain
    pfam00084
    Location:301 → 362
    Sushi; Sushi repeat (SCR repeat)
    pfam14670
    Location:153 → 181
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  6. XM_035274723.2 → XP_035130614.1  mannan-binding lectin serine protease 1 isoform X2

    UniProtKB/TrEMBL
    F7I992
    Conserved Domains (6) summary
    PHA02639
    Location:307 → 440
    PHA02639; EEV host range protein; Provisional
    smart00020
    Location:456 → 718
    Tryp_SPc; Trypsin-like serine protease
    cd00041
    Location:35 → 144
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam00084
    Location:308 → 369
    Sushi; Sushi repeat (SCR repeat)
    pfam00431
    Location:192 → 301
    CUB; CUB domain
    pfam14670
    Location:160 → 188
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  7. XM_035274724.2 → XP_035130615.1  mannan-binding lectin serine protease 1 isoform X5

    UniProtKB/TrEMBL
    F7I992
    Conserved Domains (6) summary
    PHA02639
    Location:274 → 407
    PHA02639; EEV host range protein; Provisional
    smart00020
    Location:423 → 685
    Tryp_SPc; Trypsin-like serine protease
    cd00041
    Location:2 → 111
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam00084
    Location:275 → 336
    Sushi; Sushi repeat (SCR repeat)
    pfam00431
    Location:159 → 268
    CUB; CUB domain
    pfam14670
    Location:127 → 155
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  8. XM_008981374.4 → XP_008979622.1  mannan-binding lectin serine protease 1 isoform X8

    UniProtKB/TrEMBL
    A0A2R8MS19
    Conserved Domains (4) summary
    cd00033
    Location:327 → 389
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    cd00041
    Location:54 → 163
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam00431
    Location:211 → 320
    CUB; CUB domain
    pfam14670
    Location:179 → 207
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  9. XM_008981375.5 → XP_008979623.1  mannan-binding lectin serine protease 1 isoform X9

    See identical proteins and their annotated locations for XP_008979623.1

    UniProtKB/TrEMBL
    A0A2R8MS19, F7IBP0, U3EHF2
    Related
    ENSCJAP00000026576.2
    Conserved Domains (4) summary
    cd00041
    Location:28 → 137
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam00431
    Location:185 → 294
    CUB; CUB domain
    pfam00084
    Location:301 → 362
    Sushi; Sushi repeat (SCR repeat)
    pfam14670
    Location:153 → 181
    FXa_inhibition; Coagulation Factor Xa inhibitory site

RNA

  1. XR_004734344.2 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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