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RPA1 replication protein A1 [ Callithrix jacchus (white-tufted-ear marmoset) ]

Gene ID: 100402829, updated on 8-Mar-2024

Summary

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Gene symbol
RPA1
Gene description
replication protein A1
See related
Ensembl:ENSCJAG00000001848
Gene type
protein coding
RefSeq status
MODEL
Organism
Callithrix jacchus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae; Callitrichinae; Callithrix; Callithrix
Orthologs
human mouse all
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Genomic context

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See RPA1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2023_03 current mCalJa1.2.pat.X (GCF_011100555.1) 5 NC_071446.1 (62437032..62498131, complement)
105 previous assembly Callithrix_jacchus_cj1700_1.1 (GCF_009663435.1) 5 NC_048387.1 (65113865..65174973, complement)

Chromosome 5 - NC_071446.1Genomic Context describing neighboring genes Neighboring gene reticulon 4 receptor like 1 Neighboring gene uncharacterized LOC103793020 Neighboring gene SET and MYND domain containing 4 Neighboring gene prohibitin 1-like Neighboring gene serpin family F member 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. De novo assembly of the common marmoset transcriptome from NextGen mRNA sequences. Maudhoo MD, et al. Gigascience, 2014. PMID 25243066, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables damaged DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables single-stranded telomeric DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA replication IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in DNA unwinding involved in DNA replication IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in double-strand break repair via homologous recombination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in meiotic cell cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nucleotide-excision repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in telomere maintenance via telomerase IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of DNA replication factor A complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
replication protein A 70 kDa DNA-binding subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_011100555.1-RS_2023_03

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mCalJa1.2.pat.X

Genomic

  1. NC_071446.1 Reference mCalJa1.2.pat.X

    Range
    62437032..62498131 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002747826.6 → XP_002747872.3  replication protein A 70 kDa DNA-binding subunit isoform X1

    See identical proteins and their annotated locations for XP_002747872.3

    UniProtKB/TrEMBL
    A0A8I3WNG7, U3DXL0
    Related
    ENSCJAP00000003334.1
    Conserved Domains (1) summary
    TIGR00617
    Location:2 → 612
    rpa1; replication factor-a protein 1 (rpa1)

  2. XM_035299400.2 → XP_035155291.1  replication protein A 70 kDa DNA-binding subunit isoform X4

    UniProtKB/TrEMBL
    A0A8I3X869
    Conserved Domains (1) summary
    TIGR00617
    Location:2 → 522
    rpa1; replication factor-a protein 1 (rpa1)

  3. XM_008996363.4 → XP_008994611.1  replication protein A 70 kDa DNA-binding subunit isoform X2

    UniProtKB/TrEMBL
    A0A8I3WLE9
    Conserved Domains (5) summary
    cd04474
    Location:155 → 257
    RPA1_DBD_A; RPA1_DBD_A: A subfamily of OB folds corresponding to the second OB fold, the ssDNA-binding domain (DBD)-A, of human RPA1 (also called RPA70). RPA1 is the large subunit of Replication protein A (RPA). RPA is a nuclear ssDNA-binding protein (SSB) which ...
    cd04475
    Location:285 → 385
    RPA1_DBD_B; RPA1_DBD_B: A subfamily of OB folds corresponding to the third OB fold, the ssDNA-binding domain (DBD)-B, of human RPA1 (also called RPA70). RPA1 is the large subunit of Replication protein A (RPA). RPA is a nuclear ssDNA-binding protein (SSB) which ...
    TIGR00617
    Location:2 → 581
    rpa1; replication factor-a protein 1 (rpa1)
    pfam04057
    Location:5 → 104
    Rep-A_N; Replication factor-A protein 1, N-terminal domain
    pfam08646
    Location:430 → 575
    Rep_fac-A_C; Replication factor-A C terminal domain

  4. XM_017972205.3 → XP_017827694.1  replication protein A 70 kDa DNA-binding subunit isoform X5

    UniProtKB/TrEMBL
    A0A8I3X869

  5. XM_008996364.4 → XP_008994612.1  replication protein A 70 kDa DNA-binding subunit isoform X3

    UniProtKB/TrEMBL
    A0A8I3VV06, A0A8I3X869
    Conserved Domains (5) summary
    cd04474
    Location:186 → 288
    RPA1_DBD_A; RPA1_DBD_A: A subfamily of OB folds corresponding to the second OB fold, the ssDNA-binding domain (DBD)-A, of human RPA1 (also called RPA70). RPA1 is the large subunit of Replication protein A (RPA). RPA is a nuclear ssDNA-binding protein (SSB) which ...
    cd04475
    Location:316 → 416
    RPA1_DBD_B; RPA1_DBD_B: A subfamily of OB folds corresponding to the third OB fold, the ssDNA-binding domain (DBD)-B, of human RPA1 (also called RPA70). RPA1 is the large subunit of Replication protein A (RPA). RPA is a nuclear ssDNA-binding protein (SSB) which ...
    TIGR00617
    Location:2 → 553
    rpa1; replication factor-a protein 1 (rpa1)
    pfam04057
    Location:5 → 104
    Rep-A_N; Replication factor-A protein 1, N-terminal domain
    pfam08646
    Location:459 → 547
    Rep_fac-A_C; Replication factor-A C terminal domain
Nucleotide Protein
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