GPX1 glutathione peroxidase 1 [Meleagris gallopavo (turkey)] - Gene

Summary

Gene symbol: GPX1
Gene description: glutathione peroxidase 1
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Meleagris gallopavo
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Meleagridinae; Meleagris
Also known as: Gpx-1
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 14

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
103	current	Turkey_5.1 (GCF_000146605.3)	14	NC_015024.2 (2377076..2377998)
Build 1.1	previous assembly	Turkey_2.01 (GCF_000146605.1)	14	NC_015024.1 (2807136..2808113)

Chromosome 14 - NC_015024.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables glutathione peroxidase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in glutathione metabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in hydrogen peroxide catabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in response to hydrogen peroxide	IEA Inferred from Electronic Annotation more info	PubMed
involved_in response to selenium ion	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytosol	IEA Inferred from Electronic Annotation more info	PubMed
located_in mitochondrion	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: glutathione peroxidase 1

NP_001295581.1

EC 1.11.1.9

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001308652.1 → NP_001295581.1 glutathione peroxidase 1

See identical proteins and their annotated locations for NP_001295581.1

Status: PROVISIONAL

Source sequence(s)

GQ502186

UniProtKB/TrEMBL

D2J267

Conserved Domains (1) summary

cd00340
Location:18 → 182

GSH_Peroxidase; Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per ...