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KLK7 kallikrein related peptidase 7 [ Sus scrofa (pig) ]

Gene ID: 100359349, updated on 17-Aug-2024

Summary

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Official Symbol
KLK7provided by VGNC
Official Full Name
kallikrein related peptidase 7provided by VGNC
Primary source
VGNC:VGNC:89546
See related
Ensembl:ENSSSCG00000032902
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression
Biased expression in spleen (RPKM 1.5), ovary (RPKM 0.4) and 3 other tissues See more
Orthologs
human mouse all
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Genomic context

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See KLK7 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
6
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 6 NC_010448.4 (55644627..55649000, complement)

Chromosome 6 - NC_010448.4Genomic Context describing neighboring genes Neighboring gene kallikrein related peptidase 5 Neighboring gene kallikrein related peptidase 6 Neighboring gene kallikrein related peptidase 8 Neighboring gene kallikrein related peptidase 9

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_010448.4 Chromosome 6 Reference Sscrofa11.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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Related articles in PubMed

  1. Molecular characteristics and association analysis with litter size trait for porcine KLK7 gene. Dan L, et al. Anim Biotechnol, 2020 Oct. PMID 31006337
  2. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
  3. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Molecular characteristics and association analysis with litter size trait for porcine KLK7 gene.
    Title: Molecular characteristics and association analysis with litter size trait for porcine KLK7 gene.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of antibacterial peptide production IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
kallikrein-7
NP_001182273.1
XP_020948936.1
XP_020948937.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001195344.1 → NP_001182273.1  kallikrein-7 precursor

    See identical proteins and their annotated locations for NP_001182273.1

    Status: PROVISIONAL

    Source sequence(s)
    GU373714
    UniProtKB/TrEMBL
    D3K5N6
    Conserved Domains (2) summary
    smart00020
    Location:33 → 249
    Tryp_SPc; Trypsin-like serine protease
    cd00190
    Location:34 → 252
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010448.4 Reference Sscrofa11.1 Primary Assembly

    Range
    55644627..55649000 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021093277.1 → XP_020948936.1  kallikrein-7 isoform X1

    UniProtKB/TrEMBL
    A0A287ANS1, A0A4X1VU21, A0A8D0RIJ3
    Conserved Domains (1) summary
    smart00020
    Location:33 → 249
    Tryp_SPc; Trypsin-like serine protease

  2. XM_021093278.1 → XP_020948937.1  kallikrein-7 isoform X1

    UniProtKB/TrEMBL
    A0A287ANS1, A0A4X1VU21, A0A8D0RIJ3
    Related
    ENSSSCP00000045578.1, ENSSSCT00000063704.3
    Conserved Domains (1) summary
    smart00020
    Location:33 → 249
    Tryp_SPc; Trypsin-like serine protease
Nucleotide Protein
Heading Accession and Version

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