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SPHK1 sphingosine kinase 1 [ Oryctolagus cuniculus (rabbit) ]

Gene ID: 100357790, updated on 24-Jun-2024

Summary

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Gene symbol
SPHK1
Gene description
sphingosine kinase 1
See related
Ensembl:ENSOCUG00000006579
Gene type
protein coding
RefSeq status
MODEL
Organism
Oryctolagus cuniculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Orthologs
human mouse all
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Genomic context

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See SPHK1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) Unplaced Scaffold NW_026259273.1 (340776..345152, complement)

NW_026259273.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC127488553 Neighboring gene aralkylamine N-acetyltransferase Neighboring gene ubiquitin conjugating enzyme E2 O Neighboring gene phosphoribosyl pyrophosphate synthetase associated protein 1 Neighboring gene uncharacterized LOC127488554 Neighboring gene glutamine rich 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_026259273 Unplaced Scaffold Reference UM_NZW_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Melatonin inhibits the sphingosine kinase 1/sphingosine-1-phosphate signaling pathway in rabbits with fulminant hepatitis of viral origin. Crespo I, et al. J Pineal Res, 2016 Sep. PMID 27101794
  2. Distinctive G protein-dependent signaling in smooth muscle by sphingosine 1-phosphate receptors S1P1 and S1P2. Zhou H, et al. Am J Physiol Cell Physiol, 2004 May. PMID 15075212

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables D-erythro-sphingosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to growth factor stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sphingosine biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in intracellular membrane-bounded organelle IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
sphingosine kinase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UM_NZW_1.0 Primary Assembly

Genomic

  1. NW_026259273.1 Reference UM_NZW_1.0 Primary Assembly

    Range
    340776..345152 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_051838303.1 → XP_051694263.1  sphingosine kinase 1 isoform X1

    UniProtKB/TrEMBL
    A0A5F9C8C4

  2. XM_008250912.3 → XP_008249134.2  sphingosine kinase 1 isoform X2

    UniProtKB/TrEMBL
    G1U0X4

  3. XM_051838304.1 → XP_051694264.1  sphingosine kinase 1 isoform X4

    UniProtKB/TrEMBL
    A0A5F9C8C4

  4. XM_002722929.4 → XP_002722975.2  sphingosine kinase 1 isoform X3

    UniProtKB/TrEMBL
    A0A5F9C8C4
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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