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DGKB diacylglycerol kinase beta [ Oryctolagus cuniculus (rabbit) ]

Gene ID: 100355585, updated on 10-Oct-2024

Summary

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Gene symbol
DGKB
Gene description
diacylglycerol kinase beta
See related
Ensembl:ENSOCUG00000014076
Gene type
protein coding
RefSeq status
MODEL
Organism
Oryctolagus cuniculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Orthologs
human mouse all
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Genomic context

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See DGKB in Genome Data Viewer
Location:
chromosome: Un
Exon count:
27
Annotation release Status Assembly Chr Location
RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) Unplaced Scaffold NW_026259162.1 (2947317..3718682)

NW_026259162.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene double homeobox protein A-like Neighboring gene 40S ribosomal protein S4-like Neighboring gene zinc finger MYND domain-containing protein 19-like Neighboring gene DNA-directed RNA polymerase II subunit RPB9-like Neighboring gene uncharacterized LOC127487319 Neighboring gene serine/threonine-protein kinase MARK2-like Neighboring gene serine/threonine-protein kinase MARK2-like Neighboring gene MAP/microtubule affinity-regulating kinase 3-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_026259162 Unplaced Scaffold Reference UM_NZW_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP-dependent diacylglycerol kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in diacylglycerol metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipid phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
diacylglycerol kinase beta
Names
diacylglycerol kinase, beta 90kDa

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UM_NZW_1.0 Primary Assembly

Genomic

  1. NW_026259162.1 Reference UM_NZW_1.0 Primary Assembly

    Range
    2947317..3718682
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_051832536.1 → XP_051688496.1  diacylglycerol kinase beta isoform X1

  2. XM_051832537.1 → XP_051688497.1  diacylglycerol kinase beta isoform X2

    UniProtKB/TrEMBL
    A0A5F9DAM0

  3. XM_017350433.2 → XP_017205922.1  diacylglycerol kinase beta isoform X3

    UniProtKB/TrEMBL
    A0A5F9CKF0
    Related
    ENSOCUP00000043269.1

  4. XM_051832538.1 → XP_051688498.1  diacylglycerol kinase beta isoform X4

    UniProtKB/TrEMBL
    G1T6P3

  5. XM_017350434.2 → XP_017205923.1  diacylglycerol kinase beta isoform X5

    UniProtKB/TrEMBL
    A0A5F9CKF0
    Related
    ENSOCUP00000012104.4

  6. XM_008274094.3 → XP_008272316.1  diacylglycerol kinase beta isoform X6

    UniProtKB/TrEMBL
    A0A5F9CKF0, A0A5F9DSS4
    Related
    ENSOCUP00000048791.1
    Conserved Domains (8) summary
    smart00045
    Location:569 → 749
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:427 → 548
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    COG1597
    Location:427 → 759
    LCB5; Diacylglycerol kinase family enzyme [Lipid transport and metabolism, General function prediction only]
    cd00029
    Location:244 → 293
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cd00051
    Location:152 → 221
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam00130
    Location:309 → 360
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    pfam13499
    Location:153 → 217
    EF-hand_7; EF-hand domain pair
    pfam14513
    Location:6 → 148
    DAG_kinase_N; Diacylglycerol kinase N-terminus

  7. XM_008274095.3 → XP_008272317.1  diacylglycerol kinase beta isoform X7

    UniProtKB/TrEMBL
    A0A5F9CKF0
    Related
    ENSOCUP00000034172.1
    Conserved Domains (8) summary
    smart00045
    Location:562 → 742
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:420 → 541
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    COG1597
    Location:420 → 752
    LCB5; Diacylglycerol kinase family enzyme [Lipid transport and metabolism, General function prediction only]
    cd00029
    Location:237 → 286
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cd00051
    Location:145 → 214
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam00130
    Location:302 → 353
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    pfam13499
    Location:146 → 210
    EF-hand_7; EF-hand domain pair
    pfam14513
    Location:6 → 141
    DAG_kinase_N; Diacylglycerol kinase N-terminus
Nucleotide Protein
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