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ANGPT2 angiopoietin 2 [ Oryctolagus cuniculus (rabbit) ]

Gene ID: 100353377, updated on 8-Mar-2024

Summary

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Gene symbol
ANGPT2
Gene description
angiopoietin 2
See related
Ensembl:ENSOCUG00000015377
Gene type
protein coding
RefSeq status
MODEL
Organism
Oryctolagus cuniculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Orthologs
human mouse all
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Genomic context

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See ANGPT2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) Unplaced Scaffold NW_026259165.1 (614676..673520)

NW_026259165.1Genomic Context describing neighboring genes Neighboring gene 1-acylglycerol-3-phosphate O-acyltransferase 5 Neighboring gene uncharacterized LOC127487369 Neighboring gene microcephalin 1 Neighboring gene proline-rich nuclear receptor coactivator 2-like Neighboring gene uncharacterized LOC103352243

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_026259165 Unplaced Scaffold Reference UM_NZW_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Early increase of serum angiopoietin-2 are associated with early progression to death in experimental injury. Koutsostathis S, et al. Cytokine, 2011 Dec. PMID 22024411
  2. Forward mandibular positioning enhances the expression of Ang-1 and Ang-2 in rabbit condylar chondrocytes. Jing Z, et al. Mol Med Rep, 2013 Oct. PMID 23934380

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. forward mandibular positioning enhance the expression of Ang1 and Ang2 in condylar cartilage.
    Title: Forward mandibular positioning enhances the expression of Ang-1 and Ang-2 in rabbit condylar chondrocytes.
  2. These results suggest that circulating Ang-2 participates in the pathogenesis of systemic inflammatory response syndrome after injury connected with early haemodynamic instability.
    Title: Early increase of serum angiopoietin-2 are associated with early progression to death in experimental injury.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables receptor tyrosine kinase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Tie signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in angiogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in collagen-containing extracellular matrix IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
angiopoietin-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UM_NZW_1.0 Primary Assembly

Genomic

  1. NW_026259165.1 Reference UM_NZW_1.0 Primary Assembly

    Range
    614676..673520
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002720896.4 → XP_002720942.1  angiopoietin-2 isoform X1

    UniProtKB/TrEMBL
    A0A5F9C703, G1T9B3
    Related
    ENSOCUP00000013214.2
    Conserved Domains (2) summary
    smart00186
    Location:280 → 494
    FBG; Fibrinogen-related domains (FReDs)
    cl19219
    Location:138 → 240
    DUF342; Protein of unknown function (DUF342)

  2. XM_008274180.3 → XP_008272402.1  angiopoietin-2 isoform X2

    UniProtKB/TrEMBL
    A0A5F9C703
    Conserved Domains (2) summary
    smart00186
    Location:279 → 493
    FBG; Fibrinogen-related domains (FReDs)
    cl19219
    Location:138 → 240
    DUF342; Protein of unknown function (DUF342)
Nucleotide Protein
Heading Accession and Version

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