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AARS1 alanyl-tRNA synthetase 1 [ Oryctolagus cuniculus (rabbit) ]

Gene ID: 100348310, updated on 8-Mar-2024

Summary

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Gene symbol
AARS1
Gene description
alanyl-tRNA synthetase 1
See related
Ensembl:ENSOCUG00000008872
Gene type
protein coding
RefSeq status
MODEL
Organism
Oryctolagus cuniculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Also known as
AARS
Orthologs
human mouse all
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Genomic context

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See AARS1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 5 NC_067378.1 (29189621..29209164)

Chromosome 5 - NC_067378.1Genomic Context describing neighboring genes Neighboring gene DEAD-box helicase 19B Neighboring gene 5S ribosomal RNA Neighboring gene dolichol-phosphate mannosyltransferase subunit 1-like Neighboring gene transfer RNA glycine (anticodon GCC) Neighboring gene exosome component 6

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_067378.1 Chromosome 5 Reference UM_NZW_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables alanine-tRNA ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables amino acid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables aminoacyl-tRNA editing activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in alanyl-tRNA aminoacylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tRNA modification IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
alanine--tRNA ligase, cytoplasmic

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UM_NZW_1.0 Primary Assembly

Genomic

  1. NC_067378.1 Reference UM_NZW_1.0 Primary Assembly

    Range
    29189621..29209164
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008257608.3 → XP_008255830.1  alanine--tRNA ligase, cytoplasmic

    UniProtKB/TrEMBL
    G1SW24
    Related
    ENSOCUP00000007663.3
    Conserved Domains (6) summary
    PLN02900
    Location:6 → 961
    PLN02900; alanyl-tRNA synthetase
    cd00673
    Location:7 → 254
    AlaRS_core; Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent formation of ...
    pfam02272
    Location:886 → 955
    DHHA1; DHHA1 domain
    cl02787
    Location:495 → 531
    Translation_Factor_II_like; Domain II of Elongation factor Tu (EF-Tu)-like proteins
    cl08469
    Location:525 → 753
    tRNA_SAD; Threonyl and Alanyl tRNA synthetase second additional domain
    cl10459
    Location:402 → 485
    Peptidases_S8_S53; Peptidase domain in the S8 and S53 families
Nucleotide Protein
Heading Accession and Version

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