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G6PC2 glucose-6-phosphatase catalytic subunit 2 [ Oryctolagus cuniculus (rabbit) ]

Gene ID: 100345755, updated on 8-Mar-2024

Summary

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Gene symbol
G6PC2
Gene description
glucose-6-phosphatase catalytic subunit 2
See related
Ensembl:ENSOCUG00000001370
Gene type
protein coding
RefSeq status
MODEL
Organism
Oryctolagus cuniculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Orthologs
human mouse all
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Genomic context

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See G6PC2 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 7 NC_067380.1 (64896717..64904889, complement)

Chromosome 7 - NC_067380.1Genomic Context describing neighboring genes Neighboring gene ATP binding cassette subfamily B member 11 Neighboring gene small nucleolar RNA SNORA38 Neighboring gene SPC25 component of NDC80 kinetochore complex Neighboring gene 5-azacytidine-induced protein 2-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_067380.1 Chromosome 7 Reference UM_NZW_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables glucose-6-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in gluconeogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in glucose 6-phosphate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
glucose-6-phosphatase 2
Names
glucose-6-phosphatase, catalytic, 2
islet-specific glucose-6-phosphatase-related protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UM_NZW_1.0 Primary Assembly

Genomic

  1. NC_067380.1 Reference UM_NZW_1.0 Primary Assembly

    Range
    64896717..64904889 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002712170.4 → XP_002712216.1  glucose-6-phosphatase 2 isoform X2

    UniProtKB/TrEMBL
    G1SFA2
    Related
    ENSOCUP00000001179.3
    Conserved Domains (2) summary
    COG0671
    Location:36 → 193
    PgpB; Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]
    cd03381
    Location:38 → 278
    PAP2_glucose_6_phosphatase; PAP2_like proteins, glucose-6-phosphatase subfamily. Glucose-6-phosphatase converts glucose-6-phosphate into free glucose and is active in the lumen of the endoplasmic reticulum, where it is bound to the membrane. The generation of free glucose is an ...

  2. XM_008258705.3 → XP_008256927.1  glucose-6-phosphatase 2 isoform X1

    UniProtKB/TrEMBL
    A0A5F9DG76
    Related
    ENSOCUP00000045281.1
    Conserved Domains (1) summary
    cl00474
    Location:38 → 140
    PAP2_like; PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid ...
Nucleotide Protein
Heading Accession and Version

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