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DEGS2 delta 4-desaturase, sphingolipid 2 [ Oryctolagus cuniculus (rabbit) ]

Gene ID: 100345221, updated on 10-Oct-2024

Summary

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Gene symbol
DEGS2
Gene description
delta 4-desaturase, sphingolipid 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Oryctolagus cuniculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Orthologs
human mouse all
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Genomic context

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See DEGS2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) Unplaced Scaffold NW_026258493.1 (325843..357899)

NW_026258493.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 25 member 29 Neighboring gene YY1 transcription factor Neighboring gene Enah/Vasp-like Neighboring gene microRNA mir-342

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_026258493 Unplaced Scaffold Reference UM_NZW_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables sphingolipid delta-4 desaturase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables sphingosine hydroxylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in ceramide biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sphinganine metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
sphingolipid delta(4)-desaturase/C4-monooxygenase DES2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UM_NZW_1.0 Primary Assembly

Genomic

  1. NW_026258493.1 Reference UM_NZW_1.0 Primary Assembly

    Range
    325843..357899
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_051830862.1 → XP_051686822.1  sphingolipid delta(4)-desaturase/C4-monooxygenase DES2 isoform X2

  2. XM_051830863.1 → XP_051686823.1  sphingolipid delta(4)-desaturase/C4-monooxygenase DES2 isoform X3

  3. XM_002724320.4 → XP_002724366.1  sphingolipid delta(4)-desaturase/C4-monooxygenase DES2 isoform X1

    UniProtKB/TrEMBL
    G1SJG1
    Conserved Domains (3) summary
    PLN02579
    Location:9 → 314
    PLN02579; sphingolipid delta-4 desaturase
    cd03508
    Location:26 → 314
    Delta4-sphingolipid-FADS-like; The Delta4-sphingolipid Fatty Acid Desaturase (Delta4-sphingolipid-FADS)-like CD includes the integral-membrane enzymes, dihydroceramide Delta-4 desaturase, involved in the synthesis of sphingosine; and the human membrane fatty acid (lipid) desaturase ...
    pfam08557
    Location:6 → 42
    Lipid_DES; Sphingolipid Delta4-desaturase (DES)
Nucleotide Protein
Heading Accession and Version

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