LPL lipoprotein lipase [Oryctolagus cuniculus (rabbit)] - Gene

Summary

Gene symbol: LPL
Gene description: lipoprotein lipase
See related: Ensembl:ENSOCUG00000008236
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Oryctolagus cuniculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 15

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2023_02	current	UM_NZW_1.0 (GCF_009806435.1)	15	NC_067388.1 (1574290..1602834)

Chromosome 15 - NC_067388.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:: NC_067388.1 Chromosome 15 Reference UM_NZW_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables apolipoprotein binding	IEA Inferred from Electronic Annotation more info	PubMed
enables lipoprotein lipase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in lipid metabolic process	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: lipoprotein lipase

NP_001170801.1

EC 3.1.1.34

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001177330.1 → NP_001170801.1 lipoprotein lipase precursor

See identical proteins and their annotated locations for NP_001170801.1

Status: PROVISIONAL

Source sequence(s)

FJ429312

UniProtKB/TrEMBL

A0A5F9C0Q4, D5FIT0, G1SUR7

Related

ENSOCUP00000007117.3, ENSOCUT00000008235.4

Conserved Domains (3) summary

TIGR03230
Location:32 → 472

lipo_lipase; lipoprotein lipase

cd00707
Location:36 → 333

Pancreat_lipase_like; Pancreatic lipase-like enzymes. Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation," the ...

cd01758
Location:340 → 464

PLAT_LPL; PLAT/ LH2 domain present in lipoprotein lipase (LPL). LPL is a key enzyme in catabolism of plasma lipoprotein triglycerides (TGs) and has therefeore has a profound influence on triglyceride and high-density lipoprotein (HDL) cholesterol levels in the ...