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DLST dihydrolipoamide S-succinyltransferase [ Oryctolagus cuniculus (rabbit) ]

Gene ID: 100340017, updated on 8-Mar-2024

Summary

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Gene symbol
DLST
Gene description
dihydrolipoamide S-succinyltransferase
See related
Ensembl:ENSOCUG00000015606
Gene type
protein coding
RefSeq status
MODEL
Organism
Oryctolagus cuniculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Orthologs
human mouse all
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Genomic context

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See DLST in Genome Data Viewer
Location:
chromosome: 20
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 20 NC_067393.1 (29870996..29893811, complement)

Chromosome 20 - NC_067393.1Genomic Context describing neighboring genes Neighboring gene placental growth factor Neighboring gene ribosomal protein S6 kinase like 1 Neighboring gene uncharacterized LOC103351684 Neighboring gene prospero homeobox 2 Neighboring gene YLP motif containing 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_067393.1 Chromosome 20 Reference UM_NZW_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables dihydrolipoyllysine-residue succinyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in tricarboxylic acid cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of oxoglutarate dehydrogenase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial
Names
dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UM_NZW_1.0 Primary Assembly

Genomic

  1. NC_067393.1 Reference UM_NZW_1.0 Primary Assembly

    Range
    29870996..29893811 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002719646.4 → XP_002719692.1  dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

    UniProtKB/TrEMBL
    A0A5F9CAW7, A0A5F9DC49
    Related
    ENSOCUP00000030907.1
    Conserved Domains (3) summary
    cd06849
    Location:72 → 144
    lipoyl_domain; Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid ...
    TIGR01347
    Location:72 → 450
    sucB; 2-oxoglutarate dehydrogenase complex dihydrolipoamide succinyltransferase (E2 component)
    pfam00198
    Location:235 → 448
    2-oxoacid_dh; 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
Nucleotide Protein
Heading Accession and Version

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