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ASAH2 N-acylsphingosine amidohydrolase 2 [ Bos taurus (domestic cattle) ]

Gene ID: 100336736, updated on 10-Oct-2024

Summary

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Gene symbol
ASAH2
Gene description
N-acylsphingosine amidohydrolase 2
See related
Ensembl:ENSBTAG00000003529
Gene type
protein coding
RefSeq status
MODEL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
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Genomic context

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See ASAH2 in Genome Data Viewer
Location:
chromosome: 26
Exon count:
22
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 26 NC_037353.1 (8595075..8659719, complement)

Chromosome 26 - NC_037353.1Genomic Context describing neighboring genes Neighboring gene protein kinase cGMP-dependent 1 Neighboring gene transfer RNA cysteine (anticodon ACA) Neighboring gene U6 spliceosomal RNA Neighboring gene APOBEC1 complementation factor Neighboring gene sphingomyelin synthase 1 Neighboring gene uncharacterized LOC104975938

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037353.1 Chromosome 26 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables N-acylsphingosine amidohydrolase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in ceramide catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in long-chain fatty acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sphingosine biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
neutral ceramidase; putative neutral ceramidase C
Names
N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
XP_015316081.1
XP_059737954.1
XP_059737955.1
XP_059737956.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037353.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    8595075..8659719 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015460595.3 → XP_015316081.1  putative neutral ceramidase C isoform X4

    UniProtKB/TrEMBL
    A0A3Q1MCS9
    Related
    ENSBTAP00000004585.6, ENSBTAT00000004585.6
    Conserved Domains (3) summary
    PTZ00487
    Location:98 → 775
    PTZ00487; ceramidase; Provisional
    pfam04734
    Location:100 → 606
    Ceramidase_alk; Neutral/alkaline non-lysosomal ceramidase, N-terminal
    pfam17048
    Location:608 → 775
    Ceramidse_alk_C; Neutral/alkaline non-lysosomal ceramidase, C-terminal

  2. XM_059881972.1 → XP_059737955.1  neutral ceramidase isoform X2

  3. XM_059881971.1 → XP_059737954.1  putative neutral ceramidase C isoform X1

    Related
    ENSBTAP00000075468.1, ENSBTAT00000121979.1

  4. XM_059881973.1 → XP_059737956.1  putative neutral ceramidase C isoform X3

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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