brinp1 bone morphogenetic protein/retinoic acid inducible neural-specific 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: brinp1provided by ZNC
Official Full Name: bone morphogenetic protein/retinoic acid inducible neural-specific 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-130530-847
See related: Ensembl:ENSDARG00000078302 AllianceGenome:ZFIN:ZDB-GENE-130530-847
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary: Predicted to act upstream of or within negative regulation of mitotic cell cycle and positive regulation of neuron differentiation. Is expressed in several structures, including fin bud; gill; heart; median fin fold; and nervous system. Orthologous to human BRINP1 (BMP/retinoic acid inducible neural specific 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 5

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	5	NC_007116.7 (71251627..71460556, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	5	NC_007116.6 (70479192..70688121, complement)

Chromosome 5 - NC_007116.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Brinp 1 is expressed broadly in the developing nervous system at early stages (24 hours post fertilisation), but localises to specific structures in older embryos (48-72 hpf), as has been reported in mice.
Title: Bone morphogenetic protein/retinoic acid inducible neural-specific protein (brinp) expression during Danio rerio development.

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
acts_upstream_of_or_within negative regulation of mitotic cell cycle	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within nervous system development	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within positive regulation of neuron differentiation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of cell cycle	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info

General protein information

Go to the top of the page Help

Preferred Names: BMP/retinoic acid-inducible neural-specific protein 1

Names: bone morphogenetic/retinoic acid-inducible neural specific protein 1; deleted in bladder cancer protein 1 homolog; zmp:0000000844

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001328411.1 → NP_001315340.1 BMP/retinoic acid-inducible neural-specific protein 1

Status: PROVISIONAL

Source sequence(s)

KR559027

UniProtKB/TrEMBL

A0A0G2USH3, E7FFP8

Conserved Domains (1) summary

smart00457
Location:73 → 251

MACPF; membrane-attack complex / perforin